Amphiphilic polymers with

In addition to utilizing natural ODNs in block copolymers, ODN mimics have also been studied using polymers with the capability of forming hydrogen bonds. Bazzi and colleagues (Bazzi and Sleiman 2002 Bazzi et al. 2003) have reported diblock and triblock amphiphilic polymers with diamidopyridine (DAP) and dicarboximide moieties as molecular recognition units and studied their micelle formation properties (Chart 2.4). 

Diacyllipid-polyethyleneoxide conjugates have been introduced into the controlled drug delivery area as polymeric surface modiLers for liposomes (Klibanov et al., 1990). Being incorporated into the liposome membrane by insertion of their lipidic anchor into the bilayer, such molecules can ster-ically stabilize the liposome against interaction with certain plasma proteins in the blood that results in signiLcant prolongation of the vesicle circulation time. The diacyllipid-PEO molecule itself represents a characteristic amphiphilic polymer with a bulky hydrophilic (PEO) portion and a very short but extremely hydrophobic diacyllipid part. Typically, for other PEO-containing amphiphilic block... 

Usually, the fabrication of a close - packed assembly of amphiphilic molecules at an air - water interface by the Langmuir method requires suitable subphase conditions related to the ionic species and its concentration, pH, temperature and addition of another complementary solutes. In the last case, to explore the feasibility of enhancing the interactions of some amphiphilic polymers with water soluble polymers at the air - water interface, it was studied the system of poly(monomethyl itaconate) (PMMel) as subphase stabilizer of maleic anhydride - alt - stearyl methacrylate(MA-alt-StM) monolayers at the air - water interface. 

The growth of gold, palladium, and platinum nanoparticles in the nanostructured matrix of poly(octadecylsiloxane) (PODS) was demonstrated by Bronstein et al.102 PODS, an amphiphilic polymer with nonpolar alkyl chains and hydrophilic silanol moieties (—SiOl OH) forms a bilayer nanostructure composed of these two moieties in its hydrated form. In the presence of an aqueous solution of metal salt (e.g., Na2PdCl4, K2PtCl4, AuC13), the siloxy layer absorbed metal anions by hydrogen bonding (Scheme 5.9). After reduction, the metal ions were reduced into nanoparticles, and TEM results revealed that the nanoparticles were distributed in layer structures. The sizes of the particles were measured to be about 1-2 nm, and the narrow size distribution was attributed to the volume availability within the ordered bilayers of PODS. 

Fig. 15. Examples of amphiphilic polymers with a rigid polymer backbone (polysoap behaviour not reported), a [273] b [274] c [329] d [330]...

L. Zhang, C.-H. Hu, S.-X. Cheng, R.-X. Zhuo, Hyperbranched amphiphilic polymer with folate mediated targeting property, Colloids Surf. B 79 (2010) 427 33. 

Various amphiphilic polymers with a defined block length ratio of about 1 2 polar/nonpolar have so far been applied to the preparation of polymersomes (Fig. 6.3) [6, 7]. 

Amphiphilic Polymers with Potent Antibacterial Activity, Chapter 11... 

FIGURE 2.1.2 Polymer self-assemblies based on amphiphilic polymers with different architectures, (a) Diblock copolymer, (b) triblock copolymer, (c) graft copolymer, (d) star copolymer, and (e) hyperbranched copolymer [38]. 

Poly(A-vinylamides) are another class of synthetic thermo-responsive polymers. Two of the most common polymers of this class are poly(Al-vinylpyrrolidone) (PVP) and poly(A-vinylcaprolactam) (PVCL) (Figure 1.3). PVCL is a water-soluble nonionic amphiphilic polymer with its basic unit comprising a seven-membered cyclic amide with a polar hydrophilic carboxyl group and an amide group connected directly to a hydrophobic vinyl chain. 

Hoover, J. M., Henry, R. A., Lindsay, G. A., Nee, S. F., and Stenger-Smith, J. D., Amphiphilic polymers with syndioregic main chains for second-a-der non-linear optical investigations, in Organic Materials for Non-Linear Optics III, AshweH, G. J. and Bloor, D., Eds., Royal Society of Chemistry, Cambridge, 1993, 40. 

For the formation of the double-helix structure we best consider DNA as an amphiphilic polymer with the hydrophobic interactions driving association and the hydrophilic interactions - mainly electrostatic due to phosphate groups but also hydration plays a role - opposing association. Other interactions, like hydrogenbonding and base stacking, while not driving association, control the three-dimensional structure formed. 

Linear amphiphilic polymers with carboxyl groups were also available via sequential cationic polymerization of a fimctional vinyl ether and an alkyl derivative [6]. The sequential living cationic polymerization of diethyl 2-(vinyloxy)ethylmalonate [VOEM CHf=CHOCH2CH2CH(COOCH2CH3)2]... 

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