Ammonia aniline

The rate of reaction of a series of nucleophiles with a single substrate is related to the basicity when the nucleophilic atom is the same and the nucleophiles are closely related in chemical type. Thus, although the rates parallel the basicities of anilines (Tables VII and VIII) as a class and of pyridine bases (Tables VII and VIII) as a class, the less basic anilines are much more reactive. This difference in reactivity is based on a lower energy of activation as is the reactivity sequence piperidine > ammonia > aniline. Further relationships among the nucleophiles found in this work are morpholine vs. piperidine (Table III) methoxide vs. 4-nitrophenoxide (Table II) and alkoxides vs. piperidine (Tables II, III, and VIII). Hydrogen bonding in the transition state and acid catalysis increase the rates of reaction of anilines. Reaction rates of the pyridine bases are decreased by steric hindrance between their alpha hydrogens and the substituents or... 

The 3-amino-8-oxo derivative of 1,2,4,5,7-pentaazanaphthalene (475) is known as well as various 3-substituted derivatives of the 6,8-dioxo compound. The 3-methylthio- and 3-ethylthio-6,8-dioxo derivatives and their 7-methyl and 5,7-dimethyl analogs were prepared by ring-closure. 3-Ethylthiopyrimido[4,5-e]-as-triazine-6,8-dione was 3-substituted with alkali 2N, 100°, > 30 min) or acid 2N, 100°, < 2 hr, 70% yield) and with ammonia, aniline, piperidine, or monoalkylamines (in pyridine, 115°, 4 hr, 75-85% yield). ... 

Potassium. K aw 39.102 at no 19 valence 1 soft, silvery metal, rapidly oxidized in moist air body-centered cubic structure mp 63° bp 770° d 0.862g/cc. Sol in liq ammonia, aniline, Hg and Na... 

Addition of acetone, ammonia, aniline or diphenylamine to the oxidant causes rapid exothermic reactions, with or without flame, and large amounts under confinement would explode. The trichloro analogue is similar, but less vigorous. 

Experiment.—Acetic anhydride is added to alcohol, aqueous ammonia, aniline, and phenol. A drop of concentrated sulphuric acid is added to the phenol mixture. 

Amresco acryl-40, see Acrylamide AMS, see a-Methylstyrene n-Amyl acetate, see Amyl acetate Amyl acetic ester, see Amyl acetate Amyl acetic ether, see Amyl acetate Amylene, see 1-Pentene a-n-Amylene, see 1-Pentene p-n-Amylene, see cis-2-Pentene cis-p-Amylene, see cis-2-Pentene frans-p-Amylene, see trans-2-Venlene sec-Amyl ethanoate, see Amyl acetate Amyl ethyl ketone, see 5-Methyl-3-heptanone Amyl hydride, see Pentane Amyl methyl ketone, see 2-Heptanone n-Amyl methyl ketone, see 2-Heptanone AN, see Acrylonitrile Anaesthetic ether, see Ethyl ether Anamenth, see Trichloroethylene Anduron, see Diuron Anesthenyl, see Methylal Anesthesia ether, see Ethyl ether Anesthetic ether, see Ethyl ether Anhydrous ammonia, see Ammonia Aniline oil, see Aniline Anilinobenzene, see 4-Aminobiphenyl Anilinomethane, see Methylaniline 2-Anidine, see o-Anisidine 4-Anisidine, see p-Anisidine 2-Anisylamine, see o-Anisidine... 

Good yields of secondary amines are achieved using both the methods in the reactions of aromatic and aliphatic aldehydes as well as of diaUcyl ketones and cycloalkanones with aliphatic and alicyclic amines (and ammonia). Anilines give low yields, but when 2 equiv is used in the sodium hydrogen telluride method, the yields are improved. In the reaction of ammonia with aldehydes, symmetrical secondary amines are obtained, whereas glu-taraldehyde and amines lead to N-substituted piperidines. 

Alcoholysis of the cis and trans isomers of the dihydrooxazinone 416 was performed with ethanol, n-butanol, 3-phenylbutanol, and menthol, resulting in the corresponding A-benzoylamino esters 417 in excellent yields [77H(7)301]. The aminolysis of 416 with ammonia, aniline, benzylamine, or dibutylamine gave the carboxamides 418 in 52-99% yields [77H(7)301],... 

In propellant and missile productions health hazards may arise from contact with ammonia, aniline, MeOH,furfuryl ale, hydrazine, JP-4, hydrogen peroxide and red fuming nitric acid (Ref 2), as well as other propellant ingredients such as NG, epoxy comps, polyurethanes, Amm Perchlorate etc (Ref 5)... 

R = Ph) is the most widely investigated of these compounds and serves as a suitable reference compound. Kalb and Bayer3 reported the methanol, ammonia, aniline, and sodium bisulfite adducts of this compound. The reactivity of the indolone increases when the electron density at the 2-position is reduced. In these cases (158 R = 4-nitrophenyl, 2-pyridyl, C02alkyl),49,61,62,91 the indolone adducts (175 Nu = OH, OEt) are stable and isolable the free indolones do not exist. The 2-alkylindolones (158 R = alkyl), in which the conjugation of the azomethine group is less extensive, are also very reactive. They too are only isolated as adducts (175 R = alkyl Nu = OH) with the exception of 158 (R = 1-Bu, Section IV,A,2). 

Acrolein Ammonia Aniline (aminobenzene phenylamine) poisoning Lacrimation and respiratory irritation Eye irritation and pulmonary edema Cyanosis due to methemoglobinemia, slight narcosis, and respiratory paralysis... 

Phosgene also reacts with ammonia, aniline, dimethyl aniline, etc. With ammonia it forms urea. ... 

Benzoyl Amino Compounds.—Benzoyl chloride also reacts with ammonia, aniline and amino acids yielding acid amide compounds. 

Carbon tetrachloride -Carbon disulphide Ethyl ether Ethyl alcohol Acetic acid Ethyl acetate -Ammonia -Aniline... 

In alcoholic solution, lactose reacts with ammonia, aniline, do-decylamine, urea, guanidine, and hydroxylamine, respectively, to give lactosylamine derivatives. W-Octadecyllactosylamine was formed by condensing octadecylamine with lactose in 2-propanol-water (5 3 vol./ vol.) at room temperature. Occasionally, presence of a trace of acidic catalyst, such as ammonium chloride, zinc chloride, or hydrogen chloride may be necessary, especially if the amine is a weak base. p-Amino-phenol and p-phenetidine condense with lactose under such conditions. Condensation of lactose with o-phenylenediamine gives a quinoxaline (41), which is transformed into a flavazole derivative (42) on reaction with phenylhydrazine. The existence of a molecular compound of lactose with... 

Another synthesis of azepines from azides involved the photolysis or thermolysis of aryl azides in the presence of nucleophiles. The photolysis of phenyl azide in diethylamine yielded (34%) 2-diethylamino-3/f-azepine (311) °. In the same manner 2-substituted azepines were obtained from phenyl azide and liquid ammonia, aniline and hydrogen sulphide . 

Properties Soft, silvery metal. Rapidly oxidized in moist air. D 0.862, mp 63C, bp 770C. Soluble in liquid ammonia, aniline, mercury, and sodium. 

Very interesting PHD polyols are obtained by the reaction in polyether media of TDI with primary amines and, instead of polymeric polyurea, organic diurea compounds are generated, insoluble in polyethers, in the form of a very fine dispersion. Example of amines used include ammonia, anilines and substituted anilines, and fatty amines (reactions 6.22 and 6.23). 

Ring-opening reactions of 2-phenylpyrido[3,4- /][l,3]oxazin-4-oncs with ammonia, aniline, or 3-nitroaniline afford the corresponding 3-(acylamino)pyridine-4-carboxamides, which may be cyclized thermally to give pyrido[3,4-r/]pyrimidin-4(3/f)-ones, e.g. 4.11 453... 

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