Amine oxides hydrazines

Tropolone has been made from 1,2-cycloheptanedione by bromination and reduction, and by reaction with A -bromosuccinimide from cyolo-heptanone by bromination, hydrolysis, and reduction from diethyl pimelate by acyloin condensation and bromination from cyclo-heptatriene by permanganate oxidation from 3,5-dihydroxybenzoic acid by a multistep synthesis from 2,3-dimethoxybenzoic acid by a multistep synthesis from tropone by chlorination and hydrolysis, by amination with hydrazine and hydrolysis, or by photooxidation followed by reduction with thiourea from cyclopentadiene and tetra-fluoroethylene and from cyclopentadiene and dichloroketene. - ... 

Electrophilic substitution of the ring hydrogen atom in 1,3,4-oxadiazoles is uncommon. In contrast, several reactions of electrophiles with C-linked substituents of 1,3,4-oxadiazole have been reported. 2,5-Diaryl-l,3,4-oxadiazoles are bromi-nated and nitrated on aryl substituents. Oxidation of 2,5-ditolyl-l,3,4-oxadiazole afforded the corresponding dialdehydes or dicarboxylic acids. 2-Methyl-5-phenyl-l,3,4-oxadiazole treated with butyllithium and then with isoamyl nitrite yielded the oxime of 5-phenyl-l,3,4-oxadiazol-2-carbaldehyde. 2-Chloromethyl-5-phenyl-l,3,4-oxadiazole under the action of sulfur and methyl iodide followed by amines affords the respective thioamides. 2-Chloromethyl-5-methyl-l,3,4-oxadia-zole and triethyl phosphite gave a product, which underwent a Wittig reation with aromatic aldehydes to form alkenes. Alkyl l,3,4-oxadiazole-2-carboxylates undergo typical reactions with ammonia, amines, and hydrazines to afford amides or hydrazides. It has been shown that 5-amino-l,3,4-oxadiazole-2-carboxylic acids and their esters decarboxylate. 

Fuel octane number, 72 392, 395 Fuel oil, as a petroleum product, 78 669 Fuel oil additives amine oxides, 2 473 fatty amines, 2 534 Fuel properties, of ethers, 70 574 Fuel sources, chemical industry, 70 136 Fuel spills, hydrazine, 73 588 Fuels production, hydrocracking for, 76 842-844 Fuel sulfur, 70 54... 

Carbohydrates are easily oxidized by periodate to aldehydes which react with primary amines or hydrazines. If the formed hydrazide carries a specific ligand, e.g., biotin or digoxigenin, these ligands immobilized via the blotted macromolecule are very sensitively detected by the respective enzyme conjugates. 

Acylaminoimidazole 1-oxide 276 was prepared like 3-hydroxyimidazole 1-oxide 267 replacing amine with hydrazine. Only one example has been reported but other reactions for preparation of 3-hyd roxyi midazoIe 1-oxide 267 offer opportunities for synthesis of analogues of 276 after replacement of amine with hydrazine as the starting material (2004USP248958) (Scheme 80). 

Reaction of halopyridazines with hydroxylamine to give hydroxyla-minopyridazine has been achieved only with activated compounds [79H(12)1157, 79JHC861], This has been ascribed to the low nucleo-philicity of hydroxylamine when compared to that of amines or hydrazines. A 3-hydroxylamino group reacted with bromoacetaldehyde at room temperature to give the first example of an imidazo[l,2-ft]pyridazine 1-oxide (8IT1787). 

This type of compound was prepared from aldehydes 216 by conversion into the bis(arylhydrazone) 225, which, upon reaction with copper sulfate, afforded the corresponding triazoles 227 (Scheme 48). When 216 was allowed to react with amines or hydrazines having substituents that differ from that in 216, the corresponding mixed bis(hydrazones) 228-230 were prepared. Attempted oxidation of bis(benzoylhydrazone) 231 with iodine and mercuric oxide to give 232 was investigated (80MI7). 

This work deals with the selective reduction of aromatic nitro compounds to the corresponding aromatic amines with hydrazine hydrate in the presence of catalytic amotmts of a modified iron oxide hydroxide compound. The dependence of the rate of reduction on the nature and the position of additional substituents other than the nitro group was determined. The rate is enhanced by elexAxan-withdrawing substituents and decreased by ectToordonating groups. 

Kirschning and coworkers have recently reported the synthesis of a resin-bound diketone for the sequestration of amines and hydrazines [14]. The resin-bound diketone was synthesized via oxidation of a chloromethyl resin, followed by reductive coupling with 2,4-pentadione, to provide the requisite scavenger resin. This resin was found to be more efficient than supported-aldehydes for amine and hydrazine scavenging and, furthermore, found to be selective for the scavenging of primary amines over secondary amines (Scheme 8.10). 

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