Allergens identification

Sanchez-Monge, R., Blanco, C., Diaz-Perales, A., Collada, C., Carrillo, T., Aragoncillo, C., and Salcedo, G. (1999). Isolation and characterization of major banana allergens Identification as fruit class 1 chitinases. Clin. Exp. Allergy 29, 673-680. 

Taking the history of the patient and noting the clinical symptoms and localization of the lesions are critical. Allergen identification for a patient with a possible contact allergy to cosmetics is performed by means of patch testing with the standard series, specific cosmetic-test series, the product itself, and all of its ingredients. We can only find the allergens we look for. For skin tests with cosmetic products... 

Schocker, F., Liittkopf, D., Muller, U., Thomas, P., Vieths, S., and Becker, W.M. 2000. IgE binding to unique hazelnut allergens Identification of non pollen-related and heat-stable hazelnut allergens ehciting severe allergic reactions. EurJ Nutr 39 172-180. 

NataleM, Bisson C, Monti G, et al. (2004). Cow s milk allergens identification by two-dimensional immunoblotting and mass spectrometry. Mol Nutr. Food Res., 48 363-369. 

Lee, S., Chestnut as a food allergen Identification of the major allergens and effect of gastric and intestinal fluids, J. Allergy Clin. Immunol., 113 (Suppl.l), 234S, 2004. 

Diagnostic Tools for the Identification of Anaphylaxis-Triggering Allergens... 

Ebo DG, Ahrazem O, Lopez-Torrejon G, Bridts CH, Salcedo G, Stevens WJ Anaphylaxis from mandarin (Citrus reticulata) identification of responsible allergens. Int Arch Allergy Appl Immunol 2007 144 39-43. Raap U, Schaefer T, Kapp A, Wedi B Exotic food allergy anaphylactic reaction to lychee. J Invest Allergol Clin Immunol 2007 17 199-201. 

MW, Grunwald T, Spillner E Identification, recom- 28 binant expression and characterization of the 100 kDa high molecular weight hymenoptera venom allergens Api m5 and Ves v3. Allergy 2008 63(Suppl 88) 13-14. 29... 

Milne RW, Aulfrey SJ, Heddle RJ Myrmeciapilosula (jack jumper) ant venom identification of allergens 33 and revised nomenclature. Allergy 2007 62 437-443. 

Kimber, I. and Weisenberger, C., A murine local lymph node assay for the identification of contact allergens. Assay development and results of an initial validation study, Arch. Toxicol., 63, 274, 1989. 

Kimber, I., Hilton, J. and Botam, P. A., Identification of contact allergens using the murine local lymph node assay comparison with the Buehler occluded patch test in guinea pigs, J. ofAppl. Toxicol., 10, 173, 1990. 

Magnusson, B. and Kligman, A.M., The identification of contact allergens by animal assay. The guinea pig maximization test, J. Invest. Dermatol., 52, 268, 1969. 

Hilton, J., et al., The mouse IgE test for the identification of potential chemical respiratory allergens considerations of stability and controls, J. Appl. Toxicol., 16, 165, 1996. 

Bodin, A., et al., Identification and allergenic activity of hydroxyaldehydes — anew type of oxidation product from an ethoxylated non-ionic surfactant, Contact Dermatitis, 44, 207, 2001. 

This chapter will review the application of these methods for the hazard identification and characterization of chemical allergens and, where appropriate, for the measurement of relative potency in the context of risk assessment. 

Dearman, R.J., Basketter D.A. and Kimber, I., Variable effects of chemical allergens on serum IgE concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitizers. J. Appl. Toxicol., 12, 317, 1992. 

Hilton, J. et al., Identification of chemical respiratory allergens Dose response relationships in the mouse IgE test. Toxicol. Methods, 5, 51, 1995. 

Bayard, C., Holmquist, L. and Vesterberg, O. (1996) Purification and identification of allergenic alpha (2u)-globulin species of rat urine. Biochim. Biophys. Acta 1290, 129-34. 

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