Alane Chemistry

Besides their application at the industrial level (e.g. in the Alfol process or in Ziegler—Natta polymerization catalysts), organoaluminums are the basis of various useful organic reactions. In fact, hydroalumination of acetylenes (a Cp2ZrCl2 catalyzed process when Me3Al is the metallation reagent) is particularly useful for the stereospecific synthesis of prostaglandin precursors. 

4-addition of acetylenic alanes to conjugated enone systems proceeds through a cyclic transition state and is therefore limited to enones which are able to achieve a cw-conformation, transoid olefins giving the 1,2-adduct. 

However, the 1,4-adduct can be obtained in both cases when Ni(acac)2 is added as a catalyst [73]. 

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Especially in the early steps of the synthesis of a complex molecule, there are plenty of examples in which epoxides are allowed to react with organometallic reagents. In particular, treatment of enantiomerically pure terminal epoxides with alkyl-, alkenyl-, or aryl-Grignard reagents in the presence of catalytic amounts of a copper salt, corresponding cuprates, or metal acetylides via alanate chemistry, provides a general route to optically active substituted alcohols useful as valuable building blocks in complex syntheses. 

Before beginning an academic career I was, of course, a student. My interest in chemistry and teaching was nurtured by many fine teachers at Westtown Friends School, Knox College, and the University of North Carolina at Chapel ITill their collective influence continues to bear fruit. In particular, I wish to recognize David Macinnes, Alan ITiebert, Robert Kooser, and Richard Linton. 

As we saw in Chapter 3, the founding text of modern materials science was Frederick Seitz s The Modern Theory of Solids (1940) an updated version of this, also very influential in its day, was Charles Wert and Robb Thomson s Physies of Solids (1964). Alan Cottrell s Theoretical Structural Metallurgy appeared in 1948 (see Chapter 5) although devoted to metals, this book was in many ways a true precursor of materials science texts. Richard Weiss brought out Solid State Physics for Metallurgists in 1963. Several books such as Properties of Matter (1970), by Mendoza and Flowers, were on the borders of physics and materials science. Another key precursor book, still cited today, was Darken and Gurry s book. Physical Chemistry of Metals (1953), followed by Swalin s Thermodynamics of Solids. 

Alan R. Katritzky (1, 85, 157), Florida Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200... 

R. Alan Aitken (89), School of Chemistry, University of St. Andrews, St. Andrews, Fife KYI6 9ST, United Kingdom... 

ALAN R. KATRITZKY Department of Chemistry University of Florida Gainesville, Florida... 

The reaction between a Lewis acid R3M and a Lewis base ER3, usually resulting in the formation of a Lewis acid-base adduct R3M—ER3, is of fundamental interest in main group chemistry. Numerous experiments, in particular reactions of alane and gallane MH3 with amines and phosphines ER3, have been performed [14]. Several general coordination modes, as summarized in Fig. 2, have been identified by X-ray diffraction. 

Administrative competence and scientific merit made Yngve the choice for chairman of the Department of Chemistry at Florida in 1977. He served two terms and stepped down in 1983. The six years that Ohm was busy in the chair of the department resulted in substantial changes. An endowment was secured to bring Alan Katritsky to Gainesville and two senior theoreticians. Rod Bartlett and Mike Zemer, were convinced to join the faculty. According to the surveys... 

T. H. Tsai, J. W. Lane, and C. S. Lin Temperature-Programmed Reduction for Solid Materials Characterization, Alan Jones and Brian McNichol Catalytic Cracking Catalysts, Chemistry, and Kinetics,... 

Dr. Spiller is the editor of many clinical nutrition books. Among his multiauthor books are The Methylxanthine Beverages and Foods Chemistry, Consumption, and Health Effects (Alan R. Liss, 1984), The Mediterranean Diets in Health and Disease (Van Nostrand Rheinhold, 1991), CRC Handbook of Fiber in Human Nutrition 2nd Edition (CRC Press, 1993) and CRC Handbook of Lipids in Human Nutrition (CRC Press, 1996). 

From Gilbert, R.M., The Methylxanthine Beverages and Foods Chemistry, Consumption, and Health Effects, Spiller, G., Ed., Alan Liss, Inc., 1984, 185-193. With permission. 

Spiller, G. A., The methylxanthine beverages and foods Chemistry, consumption and health effects, Chapter 6, Alan R. Liss, Inc., New York, 1984... 

Yesair D.W., Branfman A.R., Callahan M.M. Human disposition and some biochemical aspects of methylxanthines. In Spiller G.A., ed. The Methylxanthine Beverages and Foods Chemistry.Consumption and Health Effects. New York, Alan R. Liss, 1984, 215-233. 

Vol. 21 Reilctance Spectroscopy. By Wesley Wm.Wendlandt and Harry G. Hecht Vol. 22 The Analytical Toxicology of Industrial Inorganic Poisons. By the late Morris B. Jacobs Vol. 23 The Formation and Properties of Precipitates. By Alan G.Walton Vol. 24 Kinetics in Analytical Chemistry. By Harry B. Mark, Jr. and Garry A. Rechnitz Vol. 25 Atomic Absorption Spectroscopy. Second Edition. By Morris Slavin Vol. 26 Characterization of Organometallic Compounds (in two parts). Edited by Minoru Tsutsui Vol. 27 Rock and Mineral Analysis. Second Edition. By Wesley M. Johnson and John A. Maxwell Vol. 28 The Analytical Chemistry of Nitrogen and Its Compounds (in two parts). Edited by C. A. Streuli and Philip R.Averell... 

Chemicals—Environmental aspects—Mathematical models—Congresses. 2. Environmental chemistry—Mathematical models—Congresses. I. Swann, Robert L., 1944-. II. Eschenroeder, Alan, 1933—... 

Electroanalytical Stripping Methods. By Khjena Z. Brainina and E. Neyman Air Monitoring by Spectroscopic Techniques. Edited by Markus W. Sigrist Information Theory in Analytical Chemistry. By Karel Eckschlager and Klaus Danzer Flame Chemiluminescence Analysis by Molecular Emission Cavity Detection. Edited by David Stiles, Anthony Calokerinos, and Alan Townshend... 

B. M. Lichstein, and D. D. Perry The Chemistry of Alane, I. Some Observations on the Effect of the Coordinating Base on the Aluminium-Hydrogen Absorption in the Infrared. Inorg. Chem. 2, 650 (1963). 

Grafstein, D., and C. Vogel The Chemistry of Alane, VI. Preparation of an Aluminium Difluoramide from Trimethylamine-Alane and Difluor-amine. J. Amer. chem. Soc. 88, 1576 (1966). 

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