Agaricus

Agar-agar solution Agaricus bisporus Agaritine [2757-90-6]... 

In 1996, the first successful combination of an enzymatic with a nonenzymatic transformation within a domino process was reported by Waldmann and coworkers [6]. These authors described a reaction in which functionalized bicy-clo[2.2.2]octenediones were produced by a tyrosinase (from Agaricus bisporus) -catalyzed oxidation of para-substituted phenols, followed by a Diels-Alder reaction with an alkene or enol ether as dienophile. Hence, treatment of phenols such as 8-1 and an electron-rich alkene 8-4 in chloroform with tyrosinase in the presence of oxygen led to the bicyclic cycloadducts 8-5 and 8-6 in moderate to good yield (Scheme 8.1). It can be assumed that, in the first step, the phenol 8-1 is hydroxylated by tyrosinase, generating the catechol intermediate 8-2, which is then again oxidized enzy-... 

Soler-Rivas C, Moller AC, Arpin N, Olivier JM and Wichers HJ. 2000. Induction of tyrosinase mRNA in Agaricus bisporus upon treatment with a tolaasin preparation from Pseudomonas tolaasii. Physiol Mol Plant Pathol 58 95-99. 

Gill M, Strauch RJ (1984) Constituents of Agaricus xanthodermus Genevier the first naturally endogenous azo compound and toxic phenolic metabolites. Z Naturforsch C... 

Falandysz, J. and D. Danisiewicz. 1995. Bioconcentration factors (BCF) of silver in wild Agaricus campestris. Bull. Environ. Contam. Toxicol. 55 122-129. 

Waldmann et al. used tyrosinase which is obtained from Agaricus bisporus for the oxidation of phenols to give ortho-quinones via the corresponding catechols in the presence of oxygen (scheme 33).1881 A combination of this enzymatic-initiated domino process with a Diels-Alder reaction yields the functionalized bicyclic components 164 and 165 as a 33 1 mixture starting from simple p-methyl-phenol 160 in the presence of ethyl vinyl ether 163 as an electron rich dienophile via the intermediates 161 and 162 in an overall yield of 77%. 

H Fungi - Amanita phalloides and Agaricus phalloides Cyanobacteria -Lyngbya majuscula Phalloidin, phallicidin, and amanitin - toxic peptides Majusculamide D - cytotoxic peptide Microcolin A - peptide with immunosuppressive, antileukemic and protein kinase C inhibitory activity 242... 

GI reactions have occurred from ingestion of yellow-staining Agaricus species. Agaricus xanthodermus has a strong phenol-like odor and taste, and phenol has indeed been discovered in it and in a number of other Agaricus mushrooms. It is unclear, however, whether phenol or another agent is responsible for the GI upset. 

Canned mushrooms were involved in many cases of botulism. It is suggested that Agaricus bisporus may induce C. botulinum spore germination due to oxygen consumption (Sugiyama and Yang, 1975). 

Agaricus bisporus Pleurotus ostreatus Trichoderma reesei Trichoderma spp. Schizophyllum commune Aspergillus awamori Aspergillus niger Tyromyces palustris Streptomyces flavogriseus Streptomyces olivochromogenes Streptomyces spp,... 

Umar MH, Van Griensven LJLD, Morphogenetic cell death in developing pri-mordia of Agaricus bisporus, Mycologia 9 174—177, 1997. 

Figure 12. A single hypha from an agar grown culture of C. versicolor showing labeling when the primary antisera was replaced with antisera to laccase from malt agar cultures of Agaricus bisporus. Magnification x 37,800. All bars, 1 pm. All tissue was unstained and consequently of low contrast.

CH2OH, COOH) are found in the mushroom Agaricus bisporus and are metabolized to arenediazonium ions and then to aryl radicals that form the 8-Ph-dG (X = H) adduets shown in Fig. 7. Aryl hydrazines are mutagenic in bacteria, ... 

Chen, X., Romaine, C. P., Ospina-Giraldo, M. D., and Royse, D. J. (1999). A polymerase chain reaction-based test for the identification of Trichoderma harzianum biotypes 2 and 4, responsible for the worldwide green mold epidemic in cultivated Agaricus bisporus. Appl. Microbiol. Biotechnol. 52, 246-250. 

Yong, G., Leone, C., and Strothkamp, K. G. (1990). Agaricus bisporus metapotyrosinase Preparation, characterization, and conversion to mixed-metal derivatives in the binu-clear site. Biochemistry 29, 9684—9690. 

---