Adhesiveness of Transformed and Malignant Cells

Parameter Mode of alteration Tissue, cell (-organelle) References 

Protein-bound Neu5Ac decrease whole cells (Py-3T3-cells) membrane fraction (SV-40-3T3) plasma membranes (hepatoma cells) thyroglobulin (rat) malignant lung cells (mouse) Ohta et al. 1968 al 1969, Grimes 1970, 1973 Shimizu and Funakoshi 1973, Leblond-Larouche et al. 1975 Monaco and Robbins 1973 ViLAREM et al. 1981 

CMP-Neu5Ac moderate increase Morris hepatoma 7777, 3924 A Harms et al. 1973, Reutter and Bauer 1978, Grunholz 1978 

UDP-N-Acetylgluco-samine-2 -epimerase strong decrease Morris hepatomas Yoshida sarcoma, Yoshida ascites tumor Reutter et al. 1970, Kikuchi et al. 1971, Harms et al. 1973, Grunholz 1978 Kikuchi (2/. 1971 

N-Acetylmannosamine-kinase decrease Morris hepatomas, Yoshida sarcoma, Yoshida ascites hepatoma Kikuchi et al. 1971, Grunholz 1978 

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