Acetonitrile Acetylation

Acetamide MEA 2 -Acetonaphthone Acetonitrile Acetyl acetone Acrylamide Adipamide Allyl chloride Allyl methacrylate 2-(2-Aminoethoxy) ethanol N-(2-Aminoethyl)-3-aminopropyl methyidimethoxy silane (Z)-N-(2-Aminoethyl-N -(2-(2-(8-heptadecenyl)-4,5-dihydro-1 H-imidazol-1 -yl) ethyl) ethylenediamine 3-Aminopropylmethyldiethoxysilane 4-Aminopropylmorpholine Ammonium sulfite Aniline... 

Oleyl erucate PEG-20 sorbitan isostearate PPG-5-ceteth-20 PPG-10 methyl glucose ether PPG-20 methyl glucose ether SD alcohol 27-A SD alcohol 27-B SD alcohol 36 Trihydroxystearin solvent, pharmaceuticals Acetic acid Acetic acid, glacial Acetone Acetonitrile Acetylated mono- and diglycerides of fatty acids Acetyl triethyl citrate n-Amyl alcohol t-Amyl alcohol Apricot kernel oil PEG-6 esters Benzene... 

This method was designed to produce an acetyl intermediate just like that in the failed recipe a few paragraphs above using only sulfuric acid and acetonitrile [93]. This reaction works, in theory, in a so-so manner on allylbenzene but not on safrole. This method will not make X for many reasons. So why does underground literature and DEA forensic scientists keep claiming that it does Strike doesn t know either. Let s see what the man who invented this. Dr. Ritter, had to say back in 1952 "several attempts to obtain amides from...safrol (sic) were fruitless. [94]. What makes all these people think that this will work unless no one did their homework. This is another sore spot of Strike s and... 

Eused-ring polycycHc fluoroaromatics can be made from the corresponding amino fused-ring polycycHc or from preformed fluoroaromatics, eg, 4-fluorophenyl-acetonitrile [459-22-3] (275). Direct fluorination techniques have been successfully appHed to polycycHc ring systems such as naphthalene, anthracene, benzanthracenes, phenanthrene, pyrene, fluorene, and quinoHnes with a variety of fluorinating agents xenon fluorides (10), acetyl hypofluorite (276), cesium fluoroxysulfate (277), and electrochemical fluorination (278,279). 

Acetone cyanohydrin (stabilized), 6 Acetone tliiosemicarbazide, 6 Acetonitrile, 6 Acetophenetidin, 7 Acetophenone, 7 Acetyl acetone peroxide, 7 Acetyl bromide, 7 Acetyl chloride, 7... 

Dehydrochlorination of bis(tnfluoromethylthio)acetyl chloride with calcium oxide gives bis(trifluoromethylthio)ketene [5] (equation 6) Elimination of hydrogen chloride or hydrogen bromide by means of tetrabutylammonium or potassium fluoride from vinylic chlorides or bromides leads to acetylenes or allenes [6 (equation 7) Addition of dicyclohexyl-18-crown-6 ether raises the yields of potassium fluoride-promoted elimination of hydrogen bromide from (Z)-P-bromo-p-ni-trostyrene in acetonitrile from 0 to 53-71 % In dimethyl formamide, yields increase from 28-35% to 58-68%... 

The hydration of 5-amino-3-cyano-l-(2,6-dichloro-4-trifluoromethylphenyl)-4-ethynylpyrazole was performed with p-toluenesulfonic acid monohydrate in acetonitrile (2 h, room temperature) to give the corresponding 4-acetyl derivative. An alkyl substituent at the triple bond decreases the rate of hydration the conversion of 5-amino-3-cyano-l-(2,6-dichloro-4-trifiuoromethylphenyl)-4-(prop-l-yn-l-yl) pyrazole to the 4-propanoylpyrazole was completed after 18 h (98INP9804530 99EUP933363). 

Acetyl-(4-bromomethyl]benzonitrile 9. 2-Acetyl-4-bromophenyl)acetonitrile... 

Zur reduzierenden Acetylierung von 3-Phenyl-bzw. 2,3-Diphenyl- pyrido-[2,3-b]-py-razin) in Acetonitril/Acetanhydrid zu 2-Phenyl-1,4-diacetyl-1,4-dihydro- (25% d.Th.) bzw. 2,3-Diphenyl-5-acetyl-5,8-dihydro-(pyrido[2,3-b]-pyrazin) (91% d.Th.) s. Lit.2 ... 

Scheme 11.5 gives some examples of these acylation reactions. Entry 1 is an example of a chloromethylation reaction. Entry 2 is a formylation using carbon monoxide. Entry 3 is an example of formylation via to-chloromethyl ether. A cautionary note on this procedure is the potent carcinogenicity of this reagent. Entries 4 and 5 are examples of formylation and acetylation, using HCN and acetonitrile, respectively. Entries 6 to 8 are examples of Vilsmeier-Haack reactions, all of which are conducted on strongly activated aromatics. 

Figure 3. Time dependence of the fraction R of unreacted aminostyrene residues during acetylation by 0.14 M acetic anhydride at 30°C. Methyl methacrylate copolymer in acetonitrile solution (0) linear poly-(methyl methacrylate-co-butyl methacrylate) swollen with acetonitrile Cd) methyl methacrylate copolymer crosslinked with 1 mole% ( ) and with 15 mole% ( ) ethylene dimethacrylate poly(methacrylate crosslinked with 3 mole% ethylene dimethacrylate containing entrapped poly(methyl acrylate-co-aminostyrene) ( ).

Analogous derivative 338, lacking the TBDMS protection in the polyol side chain, when treated with DMAD in acetonitrile provides a mixture of unstable products, which after acetylation yields products 339-341. On the other hand, the same compound treated with DMAD in the presence of PTSA in boiling benzene gives a mixture of isomeric products 342 and 343 in a 4 1 ratio (Scheme 50) <2002T1199>. 

Acylation of the piperazine nitrogen atoms of 47/,87/-bis[l,2,5]oxadiazolo[3,4- 4 -< ]pyrazine 59 with acetyl bromide proceeds smoothly in the presence of pyridine in acetonitrile to give 60 (Equation 9) <1997CHE618>. 

The solubility of (S) 3,5-dichloro-2-hydroxy-[[2-[[[3-hydroxy-5[l, 4,5,6-tetrahy-dro-5-hydroxypyrimidin-2-yl-amino]phenyl]carbonyl]amino]acetyl]amino]-benzene-propanoic acid and its monohydrate was measured at several temperatures in different aqueous acetonitrile solvent systems [7]. The data were fitted to a frame-... 

H2S04-Si02-Promoted One-Pot Benzylidenation/Isopropylidenation-Acetylation, in Acetonitrile... 

To a cooled and stirred solution of 100 ml acetonitrile and 64.8 g mercuric nitrate, add slowly 0.2M of the allylbenzene (keep temperature below 30°). Stir one hour at room temperature, cool and add 200 ml 3N NaOH, then 200 ml 0.5M NaBH4 in 3N NaOH. After one hour saturate the water layer with NaCI and extract with ether. Dry and evaporate in vacuum the extract to get the N-acetyl-amphetamines. This procedure may not work with the propeny I benzenes. 

Fluorination with Silver Fluoride from Glycosyl Bromide [17] A mixture of 2,3,4,6-tetra- O-acetyl-a-D-glucopyranosyl bromide (5 g) and anhydrous silver fluoride (5 g) in dry acetonitrile (25 ml) was shaken under argon overnight. The resulting solution was filtered and aqueous sodium chloride was added to precipitate any silver ions from the solution. The mixture was filtered and concentrated to a syrup that was... 

Wong and coworkers showed that 5-azido sialyl donors protected with O-acetyl ester are useful for a-selective glycosylations of primary hydroxyls (Scheme 4.6e) [169]. It was proposed that the linear and electron-withdrawing nature of the C-5 azido moiety stabilizes the reactive axial acetonitrile adduct to allow the incoming nucleophile to approach the a-face in an SN2-like fashion. In addition, a chemose-lective glycosylation method has been developed for the synthesis of NeuAca-(2 —> 9) NeuAc as thioglycoside donor for use in the subsequent glycosylations [169]. 

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