Acetic acid, ethylenediamine

The most widely used titrant for such determinations is diamino-ethane-tetra-acetic acid (ethylenediamine tetra-acetic acid) which is conveniently employed as the disodium salt, referred to throughout this book as EDTA. (The titrant is referred to in the B,P, and B,P,C, as sodium edetate, but this synonym has not gained universal acceptance.) Many other amino-polycarboxylic acids have been used and in certain special applications they may have some advantage for routine pharmaceutical work, however, it has not been found necessary to use any titrant other than EDTA. This substance reacts stoichiometrically with most metals to form a 1 1 complex and, usually, the reaction is instantaneous (but see Aluminium, p. 32). pH has a marked effect on the stability of the complexes formed the alkaline earth metals form complexes that are stable in alkaline solution but decompose in neutral and acid solution aluminium, copper, lead and mercury all complex under mildly acid conditions while bismuth and ferric iron form stable complexes in a solution as acid as pH 1. The monovalent ions of sodium, potassium and silver form complexes that are too weak to be used for titration purposes whilst mercurous mercury forms no complex,... 

Hydrogen chloride Acetic anhydride, aluminum, 2-aminoethanol, ammonia, chlorosulfonic acid, ethylenediamine, fluorine, metal acetylides and carbides, oleum, perchloric acid, potassium permanganate, sodium, sulfuric acid... 

Bisamides. Methylenebisamides are prepared by the reaction of the primary fatty amide and formaldehyde in the presence of an acid catalyst. AijAT-Methylenebisoleamide has been made via this route without the use of refluxing solvent (55). Polymethylenebisamides can be made from fatty acid, esters, or acid haUdes with diamines while producing water, alcohol, or mineral acid by-products. Eatty acids and diamines, typically ethylenediamine, have been condensed in the presence of NaBH and NaH2P02 to yield bisamides (56). When stearic acid, ethylenediamine, and methyl acetate react for 6 h at... 

Note Other aromatic amines, e. g. 1- or 2-naphthylamine in acetic acid solution (Griess reagent), can be used as coupling agent instead of N-(l-naphthyl)-ethylenediamine ... 

Part of the LPS may be removed by treating the cells with ethylenediamine tetra-acetic acid (EDTA) or related chelating agents (Chapter 12). 

Chelators, especially ethylenediamine tetra-acetic acid (EDTA), have been used as potentiators of the aetion of ehloroxylenol. Vaara has extensively reviewed the subject of permeabilization and Ayres, Furr and Russell have described a rapid method of evaluating the permeabilizahon of Ps. aeruginosa (see Further Reading, Sechon 6). 

Fig. 4.1. Potential ranges of solvents, (a) h.n.p.s of acids. I, Acetic acid II, benzoic acid III, formic acid IV, salicylic acid V, sulphuric acid VI, p-toluenesulphonic acid, (b) h.n.p.s of conjugate acids of I, n-butylamine II, piperidine III, ethylenediamine (1) IV, ammonia V, ethylenediamine (2) VI, pyridine.

Ar,A,-bis(2-hydroxybenzyl)-ethylenediamine-A,A, -diacetic acid (HBED) and IV-hydroxybenzyl-ethylenediam i ne- A-, A", N -iri acetic acid (HBET) are multidentate ligands investigated for coordination with gallium and indium (Figure l).78 HBED, with its two phenolate donor groups, led to increased stability constants over HBET. 

Cobalt(II), ethylenediamine tetraacetate Acetic acid/Ethylbenzene 333 3.8 X 105 [131]... 

CEC [Chisso Engineering Company] A process for removing oxides of nitrogen from flue-gases by scrubbing with an aqueous solution containing ferrous ion and ethylenediamine tetra-acetic acid (EDTA). An iron nitrosyl compound is formed. Developed by Chisso Engineering Company, Japan, and piloted in France and Japan. 

Geigy A one-stage process for making ethylenediamine tetra-acetic acid (EDTA) from eth-ylenediamine, hydrogen cyanide, and formaldehyde. 

Before 1970, most of the data for nitrogen oxides were obtained by continuous measurements with a colorimetric analyzer that was similar in principle to the colorimetric oxidant analyzer shown in Figure 6-8. The scrubbing agent is a mixture of -(l-naphthyl)ethylenediamine, sulfanilic acid, and acetic acid in aqueous solution. The color is produced when both nitrogen dioxide and nitrites react with this reagent to form an azo dye. The color is not affected by nitric oxide in the air sample. 

A similar experiment using a diamine (ethylenediamine) as the bridging agent instead of a diacid, in combination with isobutyraldehyde and acetic acid, led to the isolation of macrocycle 114 (Scheme 20). 

A great number of ligands, such as the anions of ethylenediamine-NNN N -tetra-acetic acid (EDTA), described in detail by Schwarzen-bach and his school (29, 30), show a pronounced selectivity for alkaline earth and other metal cations (30). Because of the limited lipid solubility of these ligands and their complexes, such compounds are, however, not suited as ion carriers in lipophilic membranes (Fig. 2). The ability... 

The preparations proved to be 98 to 99% chromatographically pure, the contaminant always being the other isomer. The various absorption maxima are reported in Table I. All solutions were 0.01 M in complex. Those designated as HC or HT were measured either in water at pH 5-6, or in O.lM sodium acetate-acetic acid buffer at pH 5.5 (no spectral differences resulted) and those designated C or T were adjusted to pH 10.5 with ethylenediamine. 

Glacial acetic acid. Aluminum foil. Toluene, Methylene iodide. Acetonitrile, Tetrahydrofuran, Sodium hydroxide. Acetone, Magnesium sulfate. Aluminum chloride. Chloroform Ethylenediamine, Glyoxal, Sodium nitrite. Hydrochloric acid. Nitric acid. Ethanol 4,4,4-Trinitrobutryaldehyde, Methanol, Sodium borohydride. Hydrochloric acid. Methylene chloride. Sodium bicarbonate. Magnesium sulfate... 

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