Abnormal characteristic

A more general example from virus vaccine production is the rigorous examination of tissue cultures to exclude contamination with infectious agents from the source animal or, in the cases of human diploid cells or cells from continuous cell lines, to detect cells with abnormal characteristics. Monkey kidney cell cultures are tested for simian herpes B virus, simian virus 40, mycoplasma and tubercle bacilli. Cultures of human diploid cells and continuous line cells are subjected to detailed kary-ological examination (examination of chromosomes by microscopy) to ensure that the cells have not undergone any changes likely to impair the quality of a vaccine or lead to undesirable side-effects. 

The Grimm lamp has an abnormal characteristic, the current is selected to be at 40-200 mA and the burning voltage is usually below 1 kV. Both in krypton as well as in neon the burning voltage is higher than in argon, but it also depends on the... 

It has long been known that chromosomal abnormalities abound in tumor cells. We have already encountered several examples of oncogenes that are formed by translocation, amplification, or both (e.g., c-myc, bcr-abl, bcl-2, and cyclin Dl). Another chromosomal abnormality characteristic of nearly all tumor cells is aneuploidy, the presence of an aberrant number of chromosomes—generally too many. 

Detection method and abnormal characteristics analysis of TEM in coal mine... 

Abnormal characteristics analysis of fault fissure water detection... 

When aggregates of tumor cells achieve a diameter of 1 -2 mm, they need new blood vessels, or neovasculature, to supply nutrients and oxygen [37]. These newly formed vessels usually have irregular and incomplete architectures and impaired physiological responses [37-41]. Table 1 siunmarizes the abnormal characteristics of tumor vessels. 

Table 1 Abnormal characteristics and factors of solid tumors that influence the EPR effect of macromolecular drugs in vivo...

A.M. Simon, D.A. Goodenough, D.L. Paul, Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block, CurrBiol 8 (1998) 295-298. 

Rheumatoid arthritis (RA) is a multisystem disorder in which immunological abnormalities characteristically result in symmetrical joint inflammation, articular erosions and extra-articular complications. It is the most common and disabling autoimmune arthritis, and genetic susceptibility is well defined. The production of increased amounts of IgG and the presence of rheumatoid factor (immunoglobulins directed against the Fc portion of IgG) are two characteristic features associated with RA [36]. 

Sundaresan V, Ganly P, Hasleton P, et al. p53 And chromosome 3 abnormalities, characteristic of malignant lung turnouts, are detectable in preinvasive lesions of the bronchus. Oncogene 1992 7 1989-1997. 

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