A phage

Anderson, J.E., Ptashne, M., Harrison, S.C. A phage repressor-operator complex at 7 A resolution. Nature 316 S96-601, 1985. 

Murialdo, H., 1991. Bacteriophage lambda DNA maturation and packaging. Annual Review of Biochemistry 60 125-153. Review of the biochemi.stry of packaging DNA into A phage heads. 

Fig. 3.4 Plaques formed by a phage on a plate seeded viith Bacillus subtilis. 

Cochrane, D., Webster, C., Masih, G., and McCafferty, J. (2000). Identification of natural ligands for SH2 domains from a phage display cDNA library. J. Mol. Biol. 297, 89-97. 

Stringer, J. Development of a phage-typing system for group-B streptococci. J. Med. Microbiol. 1980,13,133-143. 

Mainly the outer membrane ferrichrome receptor and transporter FhuA will be discussed because most structural and functional studies have been performed with this protein. In fact, FhuA was the first outer membrane protein identified (called TonA), with known functions as a phage and colicin receptor, that are related to iron transport (for a historical account, see Braun and Hantke 1977). 

We have previously developed an in vivo selection method in which peptides that home to specific vascular beds are selected after intravenous administration of a phage display random peptide library [5]. This strategy revealed a vascular address system that allows tissue-specific targeting of normal blood vessels [6-8] and angiogenesis-related targeting of tumor blood vessels [3, 6, 9-12]. While the biologi-... 

Figure 16.4 Graph depicting the percentage of lysine residues among peptides that bind to the indicated monoclonal antibodies. The peptides were isolated after affinity selection (biopanning) from a phage-displayed combinatorial peptide library. The peptides are grouped as to whether they are susceptible to formalin fixation, resulting in a loss of immunoreactivity.

The conformational behaviour in solution of a dermatan-derived tetra-saccharide has been explored by means of NMR spectroscopy, especially by NOE-based conformational analysis. RDCs were also measured for the tetrasaccharide in a phage solution and interpreted in combination with restrained MD simulations. The RDC-derived data substantially confirmed the validity of the conformer distribution resulting from the NOE-derived simulations, but allowed an improved definition of the conformational behaviour of the oligosaccharides in solution, which show a moderate flexibility at the central glycosidic linkage. Differences in the shapes of the different species with the IdoA in skew and in chair conformations and in the distribution of the sulphate groups were also highlighted.28... 

De Martino, T., Minenkova, O., Bombardi, V, Anastasi, A. M., Lindstedt, R., Felici, F., De Santis, R., Verdoliva, A. Identification and refinement of a peptide affinity ligand with unique specificity for a monoclonal anti-tenascin-C antibody by screening of a phage display library. / Chromatogr A 2006, 1107, 182-191. 

Leverentz, B., Conway, W. S., Janisiewicz, W., and Camp, M. J. (2004). Optimizing concentration and timing of a phage spray application to reduce Listeria monocytogenes on honeydew melon tissue. /. Food Prot. 67,1682-1686. 

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