A-glycerolphosphate

If we assume completion of the reaction when been converted to P (a-glycerolphosphate), then... 

Glucose metabolism in glycosomes of trypanosomes (a) Glycerolphosphate kinase (b) Glycerol kinase. 

Malate and a-glycerolphosphate shuttles. The shuttling of reducing power from cytosolic NADH into the mitochondrion. The malate shuttle (top portion) is more complex, but yields more highenergy phosphates. Malate can move reducing power into or out of the mitochondria. The a-glycerolphosphate shuttle only moves reducing power from the cytosol to the mitochondria. 

Triglyceride and phospholipid formation. This figure depicts the formation of triacylglycerol from a-glycerolphosphate and fatty-acyl CoA. The formation of phosphatidylethanolamine and phosphatidylcholine from scratch (i.e., from serine and methionine methyl groups) is also shown. The formation of phosphatidylcholine, starting with choline, is also depicted and is the major pathway for phosphatidylcholine synthesis. 

The second type of a-glycerolphosphate dehydrogenase was first described by Green" as a particulate system which was coupled to cytochrome c. This particulate system has now been solubilized by treatment with sodium desoxycholate. On further purification the enzyme was separated from triosephosphate dehydrogenase, isomerase, and catalase activities and no longer was capable of reducing cytochrome c. It also did not react with DPN, TPN, or FAD, although it readily reduced suitable dyes. The reaction product was dihydroxyacetone phosphate. 

L-a-glycelophosphoric acid L-lactic acid L-a-glycerolphosphate oxidase lactate oxidase 26)... 

A recent report by Coldfine (1966) has implicated AGP in the biosynthesis of lysophosphatidic add from palmitoyl CoA and a-glycerolphosphate. The reaction involves both soluble and particulate cell fractions of E. coli extracts. This interesting finding raises the question of the possible function of acyl AGP derivatives in biosynthesis of the basic backbone of all the bacterial lipids (cf.. Section III, B, 1). 

The first step in the respiratory consumption of fats is a hydrolysis, catalysed by the enz)rme neutral lipase which results in the release of glycerol and free fatty acids. The glycerol is phosphorylated to a-glycerolphosphate, and then converted to dihydroxyacetonephos-phate, a point of entry into the EMP and pentosephosphate pathways. 

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