Zearalenone Gibberella zeae

Gaffoor, I., and Trail, F. (2006). Characterization of two polyketide synthase genes involved in zearalenone biosynthesis in Gibberella zeae. Appl. Environ. Microbiol. 72,1793-1799. 

Zearalenone (119) is a 14-membered resorcylic keto lactone isolated from the fungus Gibberella zeae. - Anabolic and uterotrophic activity have been exhibited by this compound. 

Agriculture Zearalenone Gibberellins Gibberella zeae G. fujikuroi Growth promoter for cattle Plant hormones... 

Ichinoe M, Kurata H, Sugiura Y, Ueno Y (1983) Chemotaxonomy of Gibberella zeae with Special Reference to the Production of Trichothecenes and Zearalenone. Appl Environ Microbiol 46 1364... 

Logrieco A, Bottalico A, Altomare C (1988) Chemotaxonomic Observations on Zearalenone and Trichothecene Production by Gibberella zeae from Cereals in Southern Italy. Mycologia 80 892... 

Zearalenone (ZEA), a 14-membered resorcylic acid lactone, was first isolated in 1962 from the Gibberella zeae, an anamorph Fusarium graminearum [111]. Structure 145 was proposed some years later (Figure 7.44) [112]. ZEA is also produced by several other Fusarium species, including Fusarium culmorum, Fusarium... 

The toxic metabolite of Gibberella zeae, zearalenone (39), elicits strong ureo-trophic activity [304]. From G. zeae cultures, four other products related to zearalenone have been isolated [305-307] and another derivative from a culture of Fusarium monoliforme. These products show some oestrogenic activity. 

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