Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Y-aminobutyric acid receptor

The aforementioned polymer-supported bis-pyridyl ligand has also been applied in microwave-assisted asymmetric allylic alkylation [140], a key step in the enantio-selective synthesis of (R)-baclofen (Scheme 7.118), as reported by Moberg and coworkers. The ( (-enantiomer is a useful agonist of the GABAb (y-aminobutyric acid) receptor, and the racemic form is used as a muscle relaxant (antispasmodic). Under microwave heating, the enantioselectivity could be improved to 89% when using toluene as solvent (see also Scheme 6.52) [140],... [Pg.376]

M. (1995) Deficiency of the P3 subunit of the type A y-aminobutyric acid receptor causes cleft palate in mice. Nature Genetics 11, 344-346. [Pg.109]

Chan-Palay, V. (1978) Autoradiographic localization of y-aminobutyric acid receptors in the rat central nervous system by using (3H)muscimol. Proc. Natl. Acad. Sci. USA, 75 1024-1028. [Pg.89]

Boileau AJ, Kucken AM, Evers AR, Czajkowski C. 1998. Molecular dissection of benzodiazepine binding and allosteric coupling using chimeric y-aminobutyric acid receptor subunits. Mol Pharmacol 53 295. [Pg.438]

Abalis IM, Eldefrawi ME, Eldefrawi AT. 1985. High-affinity stereospecific binding of cyclodiene insecticides and y-hexachlorocyclohexane to y-aminobutyric acid receptors of rat brain. Pestic Biochem Physiol 24 95-102. [Pg.129]

Majewska MD, Schwartz RD Pregnenolone-sulfate an endogenous antagonist of the y-aminobutyric acid receptor complex in brain Brain Res 404 355-360, 1987 Majewska MD, Harrison NL, Schwartz RD, et al Steroid hormone metabolites are barbiturate-hke modulators of the GABAa receptor. Science 232 1004-1007, 1986... [Pg.688]

Casida JE, Tomozawa M (2008) Insecticide Interaction with y-Aminobutyric Acid and Nicotinic Receptors Predictive Aspects of Stractural Models. J Pestic Sci 33 4 Chen LG, Durkin KA, Casida JE (2006) Stractural Model for y-Aminobutyric Acid Receptor Noncompetitive Antagonist Binding Widely Diverse Structures Fit the Same Site. Proc Nat Acad Sci USA 103 5185... [Pg.209]

The idiosyncratic toxicity, manifested by neurological effects, shown by a subpopulation of (rough-haired) Collies to ivermectin (> 100 gg/kg, p.o.) may be attributed to a breed-related compromised blood-brain barrier (Tranquilli et al, 1989), since y-aminobutyric acid receptors that mediate neurotransmission are confined to the CNS in mammalian species. The pharmacokinetic behaviour of ivermectin does not differ between ivermectin-sensitive and... [Pg.6]

Martin ER, Menold MM, Wolpert CM, Bass MP, Donelly SL, Ravan SA, Zimmerman A, Gilbert JR, Vance JM, Maddox LO, Wright HH, Abramson RK, DeLong GR, Cuccaro ML, Peiicak-Vance MA (2000) Analysis of linkage disequilibrium in y-aminobutyric acid receptor subunit genes in autistic disorder. Am J Med Genet 96 43-48. [Pg.92]

Extrapyramidal side-effects y-Aminobutyric acid receptor, type A Gastrointestinal tract Genitourinary... [Pg.17]

Data not established GABAa y-Aminobutyric acid receptor subtype... [Pg.152]

See other pages where Y-aminobutyric acid receptor is mentioned: [Pg.456]    [Pg.144]    [Pg.6]    [Pg.137]    [Pg.48]    [Pg.356]    [Pg.241]    [Pg.62]    [Pg.448]    [Pg.529]    [Pg.101]    [Pg.119]    [Pg.139]    [Pg.634]    [Pg.506]    [Pg.161]    [Pg.748]    [Pg.1800]    [Pg.1327]    [Pg.23]    [Pg.634]    [Pg.16]    [Pg.126]    [Pg.456]    [Pg.538]    [Pg.201]    [Pg.358]    [Pg.201]    [Pg.268]   
See also in sourсe #XX -- [ Pg.175 , Pg.176 , Pg.177 , Pg.178 , Pg.179 , Pg.180 , Pg.181 , Pg.182 , Pg.183 , Pg.184 , Pg.185 ]



SEARCH



2- aminobutyrate

7-Aminobutyric acid receptors

Aminobutyric

Aminobutyric acid

Y Aminobutyric acid

Y-Aminobutyrate

Y-Aminobutyric acid receptor inhibition of EBOB binding

Y?2-receptors

© 2024 chempedia.info