Wound dressings chitosan fibres

KytoCel by Aspen, reported by Aspen (2014), is a highly absorbent dressing composed of natural, biodegradable acylated chitosan fibres, which bond with wound exudate to form a clear gel that locks in fluid, absorbs pathogens, and is conformable to the wound bed. 

Textile materials can be used in moist wound management as fibres themselves (advanced fibres such as alginate and chitosan fibres), or conventional/advanced fibres can be modified or coated with various substances such as honey or hydrogels to obtain special properties such as ultra-absorbency, drag release, etc. In general, textiles used in wound-dressing products come in all possible forms, including fibres, nanofibres, filaments, yarns, and woven/knitted/non-woven and composite materials. 

Knill, C.J., Kennedy, J.F., Mistry, J., Miraftab, M., Smart, G., Groocock, M.R., Williams, HJ., 2004. Alginate fibres modified with unhydrolysed and hydrolysed chitosans for wound dressings. Carbohydrate Polymers 55 (1), 65—76. 

C J Knill, J F Kennedy, J Mistry, M Miraflab, G Smart, M R Gioocock and H J Williams, Alginate fibres modified with imhydrolysed and hydrolysed chitosan for wound dressings . Carbohydrate Polymers, Jan 2004 55 issue 165-76. 

Miraftab et al, Alginate fibres modified with unhydrolysed and hydrolysed chitosans for wound dressings. Carbohydrate Polymers , 2004 55(1) 65-76. 

To enhance the biomedical capabilities of chitosan, alginate, another natural polysaccharide extracted from brown sea weed, which has been used as wound dressing for a number of years, has recently been successfully combined with chitosan to generate hybrid fibres with superior properties of high liquid absorption, antimicrobial, anticoagulant and wound healing. Research at University of Bolton has developed this concept and acquired the universal patent for its imminent commercial exploitation (Miraftab et al., 2008 Miraftab et al., 2011, p345)... 

Gupta, B.S., Saxena, S., Arora, A., Mohammad, S., 2011. Chitosan-polyethyleue glycol coated cotton membranes for wound dressings. Ind. J. Fibre Text. Res. 36, 272 280. 

Barnabas, J., Miraftab, M., Qinand, Y., Changiun, Z. (2014). Evaluating the antimicrobial properties of chitosan fibres embedded with copper ions for wound dressing applications. Journal of Industrial Textiles, 44(2), 232—244. 

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