Wound debridement

When considering antimicrobial therapy in a patient with fever, one should answer the following questions. First, is the fever caused by an infection If affirmative, data are needed to determine the severity of the infection, the site of infection, and the causal micro-organism(s). Second, when the cause of the fever is infectious, one should ask is treatment with antimicrobial drugs needed Many soft tissue infections including impetigo and decubital ulcers are best treated with local antiseptics and/or wound debridement without the use of antibiotics. If the chance to cure the infection with antimicrobial... 

Papain—a plant protease derived from the papaya fruit. The enzyme is used in digestive aids, wound debridement, tooth-cleaning and. most importantly, as a meat tenderizer. 

Yan AC, Newman RD. Bupivacaine-induced seizures and ventricular fibrillation in a 13-year-old girl undergoing wound debridement. Pediatr Emerg Care 1998 14(5) 354—5. 

Papain has reached clinical trials for treating leg venous ulcers seen in severe diabetes. An experimental drug containing papain is being tested for safety in treating skin irritation, changes in wound debridement status, and use in possible skin grafts. 

SUtilains [ban, inn, usan] (BAX 1515 Travase ) is an ENZYME derived from Bacillus subtilis. It is a proteolytic enzyme used for wound debridement in moist conditions, suxamethonium chloride [ban. inn] (succinyichoiine chloride [usan] suxamethonium bromide [ban] succinoylcholine Scoline Quelicin Anectine ) is a bistrimethylethanaminium derivative, a NICOTINIC CHOLINOCEPTOR AGONIST, a (depolarizing) NEUROMUSCULAR BLOCKING AGENT, which can be used as a SKELETAL MUSCLE RELAXANT in anaesthesia relaxant. Its action is short-lived due to hydrolysis by plasma cholinesterase, suxamethonium bromide suxamethonium chloride. 

For wound botulism, antibiotic (penicillin) treatment is indicated, along with wound debridement and irrigation. 

Key words wound, debridement, dressing, antibacterial, antiodour, venous leg ulcer, padding bandage, compression bandage, spacer fabric bandage. 

Attinger, C.E., Janis, J.E., Steinberg, J., Schwartz, J., Al-Attar, A., Couch, K., 2006. Clinical approach to wounds debridement and wound bed preparation including the use of dressings and wound-healing adjuvants. Plast. Reconstr. Surg. 117, 72-109. 

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