Why Optimize

Why are engineers interested in optimization What benefits result from using this method rather than making decisions intuitively Engineers work to improve the initial design of equipment and strive to enhance the operation of that equipment once it is installed so as to realize the largest production, the greatest profit, the 

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Sheppard GS, Bouska JJ (2005) Why optimize cancer drugs fro ADMET Drug Discov Today Ther Strateg 2 343-349... 

Material optimization software is an advanced technology that provides companies with a ready-to-use tool to attack the high cost of scrap and inventory. This chapter discusses various material optimization software technologies for coils and sheets, and explains why optimization is becoming a large part of the cost-reduction efforts of many companies. 

Plots of economic potential versus reactor conversion allow the optimal reactor conversion for a given flowsheet to be identified (Fig. 8.2). Although this approach allows the location of the optimum to be found, it does not give any indication of why the optimum occurs where it does. 

In the APh-2-MV2+ system, a tight ion pair can be formed because the motional freedom of the Phen+ residue and a free access of MV + to the Phen + site allow the ion pair to realize an optimal distance and orientation, thus giving rise to a shorter-lived geminate ion pair. This explains why the back ET in the... 

In some cases the performance optimization of binary and ternary mixed active systems is well documented, and it is clear from the performance synergy as to why a certain combination is used. However, in recent years mixed active formulations have become more complicated, containing up to five or six surfactant components. In these cases the performance benefits of a particular mixed active system are less well defined to anyone but the actual producer of that product. 

In an earlier section, we had alluded to the need to stop the reasoning process at some point. The operationality criterion is the formal statement of that need. In most problems we have some understanding of what properties are easy to determine. For example, a property such as the processing time of a batch is normally given to us and hence is determined by a simple database lookup. The optimal solution to a nonlinear program, on the other hand, is not a simple property, and hence we might look for a simpler explanation of why two solutions have equal objective function values. In the case of our branch-and-bound problem, the operationality criterion imposes two requirements ... 

What are the optimal conditions for an exothermic reaction and why can they not always be fulfilled ... 

Actually, why do we need log D models Why can t we use just log P models One of the main requirements for prediction of octanol-water coefficients is to optimize bioavailability of chemical compounds. During the absorption process the... 

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