Watt synthesis

Dunlap Sabol Watt Tetrahedron Lett. 1984, 25. 5839 Dcmir Sayrac Watt Synthesis 1990, 1119. 

JM Evans, CS Fake, TC Hamilton, RH Poyser, EA Watts. Synthesis and antihypertensive activity of substituted trans-4-ami no-3,4-di hydro-2,2-dimethy 1-2H-1-benzopyran-3-ols. J Med Chem 26 1582-1589, 1983. 

The synthesis of [Co(edda)(C03)] was first reported by Mori et al. " but was found to be nonreproducible by Van Saun and Douglas. Recent reports by Garnett et al. show that the isomeric composition is primarily asym-cis. All the reported syntheses are based on the reaction of [00(003)3] with the free acid HjCdda. The modification employed in this synthesis involves the addition of sufficient HOI to prevent the formation of NaH003, which may contaminate the product recovered from the Garnett and Watts synthesis. ... 

Watts AG, Withers SG (2004) The synthesis of some mechanistic probes for sialic add processing enzymes and the labeling of a sialidase from Trypanosoma rangeli. Can J Chem 82 1581-1588 Watts AG, Oppezzo P, Withers SG, Alzari PM, Buschiazzo A (2006) Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase. J Biol Chem 281 4149-4155... 

Watts, P., Wong, S. Y. F., Zhang, X., Micro reactors principle and applications in organic synthesis. Tetrahedron 58, 24 (2002) 4735-4757. 

Haswell, S.T., Watts, P., Green chemistry synthesis in micro reactors. Green Chem. 5 (2003) 240-249. 

Watts, P., Wiles, G., Haswell, S. J., PoMBO-ViLiAR, E., Solution phase synthesis of f-peptides using micro reactors. Tetrahedron 58, 27 (2002) 5427-5439. 

Watts, P., Wiles, C., Haswell, S. )., PoMBO-ViLLAR, E., Investigation of racemization in peptide synthesis within a micro reactor. Lab. Chip 2 (2002) 141-144. 

Finally, the number of steps in the strigol synthesis could be reduced by the direct conversion of Xa to Xlla. To this end, Xa was treated with 1.2 equivalents of NBS in refluxing carbon tetrachloride under the irradiation of a 150-watt lamp. Purification of the crude product mixture by thin layer chromatography afforded two products Ila (27%) and the unanticipated bromoketone XV (31%). The reaction... 

Fletcher PDI, Haswell SJ, Pombo-Villar E, Warrington BH, Watts P, Wong SYF, Zhang XL (2002) Microreactors Principles and Applications in Organic Synthesis. Tetrahedron 58 4735-4757... 

Watts P, Haswell SJ (2005) The Application of Microreactors for Organic Synthesis. Chem Soc Rev 34 235-246... 

Watts P, Wiles C, Haswell SJ, Pombo-ViUar E, Styring P (2001) The Synthesis of Peptides Using Microreactors. Chem Comm 11 990-991 Watts P, Wiles C, Haswell S, Pombo-Villar E (2002a) Investigation of Racemi-sation in Peptide Synthesis within a Microreactor. Lab Chip 2 141-144 Watts P, Wiles C, Haswell S, Pombo-Villar E (2002b) Solution Phase Synthesis of Beta-Peptides Using Microreactors. Tetrahedron 58 5427-5439... 

Nikbin N, Watts P (2004) Solid-supported continuous flow synthesis in micro-reactors using electroosmotic flow. Org Process Res Dev 8 942 Overbeek JTG (1952) Electro chemistry of double layer. In Kruyt HR (ed) Colloid science, Vol. 1. Elsevier, Amsterdam... 

Watt and Drummond, were considered to be inert for C-C bond forming reactions. However, by the expedient of transmetallation to Cu, Ni, Zn, Li, and Al, methodologies for the stereoselective synthesis of olefins and dienes, as well as unusual heterocycles, aromatics and their ring-annulated products are now available which are beginning to make impact on material science, e. g. synthesis of pentacenes and polyphenylenes. Takahashi and Li provide evidence that, with further developments in transmetallation and handling the zirconacycles outside of the Schlenk tube techniques, synthetic utility will increase and new catalytic reactions will be developed. 

FuelCell Energy is a partner with Versa Power Systems, Nexant, and Gas Technology Institute to develop more affordable fuel-cell-based technology that uses synthesis gas from a coal gasifier. The key objectives include the development of fuel cell technologies, fabrication processes, and manufacturing capabilities for solid oxide fuel cell stacks for multi-mega-watt power plants. 

Only a trace of the corresponding cubane 167 is formed on irradiation of the tricy-clooctadiene 168 in pentane at ambient temperatures using a 125-watt mercury arc lamp. The principal product 169 is the result of rearrangement within a biradical intermediate79. A review of the synthetic approaches to cubane and to its reactions has been published77. The diene 170 photochemically converts on irradiation in pentane solution at 254 nm to yield a photostationary mixture of the cubane 171, the starting material 170 and the isomeric diene 17280. Other additions of this type have been used for synthesis of the propellaprismane 173, essentially a heavily substituted cubane, by the intramolecular (2 + 2)-photocycloaddition of the diene 17481. 

Watt, G. M. Revers, L. Webberley, M. C. Wilson, I. B. H. Fhtsch, S. L., Efficient enzymatic synthesis of the core trisaccharide of N-glycans with a recombinant beta-mannosyltransferase. Chem. Int Ed. 1997,36, 2354-2356. 

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