Vomiting ipecac

The emetic (a drug that induces vomiting) ipecac causes vomiting because of its local irritating effect on the stomach and by stimulation of the vomiting center in the medulla... 

Other people turn to a different method of forced weight loss. Individuals with bulimia, an eating disorder in which vomiting is induced after eating in order to prevent food from being absorbed by the body, sometimes use drugs as part of their illness. In particular, a medicinal syrup called ipecac causes abusers to vomit. Ipecac, an... 

Pharmacological treatment involves administering an emetic to induce vomiting. Ipecac is the most commonly used emetic. Ipecac, available over the counter, should be purchased as a syrup—not a fluid extract. The symp induces vomiting by stimulating the CTZ in the medulla and acts directly on the gastric mucosa. 

Ipecac is prepared from the dried roots and rhizomes of Cephaelis ipecacuanha (Brot.) A. Rich, and contains the alkaloids emetine [483-18-1] (17) and cephaeJine [483-17-0] (18) in a ratio between 2 1 and 4 1. It has been used extensively in cough preparations and is beheved to act by gastric reflex stimulation. Toxic effects include vomiting, irritation of the gastrointestinal tract, and cardiac arrhythmias (19). Ipecac symp is available over-the-counter in the United States only in 30-mL containers for use as an emetic in treating poisonings. 

The most widely used emetic is syrup of ipecac, containing the alkaloids, emetine and cq haeline. Emetine induces vomiting by activation of sensory neurons in the vagus and sympathetic nerves to the stomach and centrally in the medulla, possibly at the CTZ. The release of serotonin and SP may be involved as 5-HT3 and NKi receptor antagonists prevent emesis induced... 

Ingestion Induce vomiting by having victim touch the back of his throat with finger or by giving victim symp of ipecac as directed do not induce vomiting if victim is unconscious seek medical attention immediately. 

Treatment — As with other toxin therapies, treatment is limited mainly to supportive management. Mechanical respiration support may be required in severe cases. An antitoxin has shown success in animal models, but no human data are available to date. No vaccine has been developed. Induction of vomiting may prove to be useful as part of the treatment program. Ipecac syrup is a good emetic that could be used to induce vomiting.3... 

No vaccine has been developed Induction of vomiting may prove to useful Ipecac syrup can induce vomiting... 

Syrup of ipecac is the method of choice outside the hospital. Do not induce vomiting if the medication is caustic or a petroleum or if the patient is in a coma or having seizures. Syrup of ipecac takes 20 to 30 minutes to work. Consider gastric lavage if response is needed immediately. 

Ipecac Alkaloid Induces vomiting Psychotria ipecacuanha... 

B. Two medicines, ipecac and apomorphine, induce vomiting. Metoclopramide is a prokinetic with antiemetic properties and therefore would have the opposite of the desired effect. Morphine is an opioid with analgesic and sedating properties. Promethazine and ondansetron are also antiemetics, not emetics. 

Cardiotoxicity may occur if ipecac syrup is not vomited (noted as hypotension, tachycardia, precordial chest pain, pulmonary congestion, dyspnea, ventricular tachycardia and fibrillation, cardiacarrest). 

Most patients with BN can be effectively treated as outpatients. Medical hospitalizations result from consequences of purging activities, such as frequent vomiting and abuse of laxatives and diuretics, which can create electrolyte imbalances and dehydration. These patients are at risk for developing cardiac arrhythmias due to hypokalemia. If the patient s serum potassium falls below 2.5 mEq/T, the patient should be hospitalized. Other medical emergencies are gastric dilatation and esophageal tears (both are rare). Cardiac failure caused by cardiomyopathy from ipecac intoxication is a medical emergency. 

Emetics are used to induce vomiting and are frequently administered to help empty the stomach of poisons or ingested toxins. The two primary emetics are apo-morphine and ipecac. Both agents seem to work by stimulating the medullary emetic center, and ipecac also exerts a direct emetic effect on the stomach. 

The efficacy of ipecac in amebic infections depends upon its content of alkaloids, the principal ones being emetine and cephaeline. Both are amebicidal, but emetine is much more active. Cephaeline is more toxic than emetine, except for the heart, and causes more nausea and vomiting. Emetine constitutes more than one half of the total alkaloidal content of ipecac. 

There are a few important drugs that cause nausea and vomiting as undesirable side actions when used in therapeutic dosage, and perhaps a larger number that induce the state as part of a serious toxic reaction to them in overdosage, but the number that is used intentionally to cause the patient to vomit is relatively small. Here, the following four — ipecac, apomorphine, mustard, copper sulfate — are considered as a group. 

Vomiting can be induced mechanically by stroking the posterior pharynx. However, this technique is not as effective as the administration of ipecac or apomorphine. 

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