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Alkaloids ipecac

Ipecac Alkaloid Induces vomiting Psychotria ipecacuanha... [Pg.28]

Fujii T and Ohba M (1998) The ipecac alkaloids and related bases. The Alkaloids, Chemistry and Biology (ed Cordell GA) Vol 51. Academic, San Diego, pp 271-321. [Pg.400]

Emetine [EM e teen] and dehydroemetine [de hye dro EM e teen] are alternate agents for the treatment of amebiasis. They inhibit protein synthesis by blocking chain elongation1. Intramuscular injection is the preferred route. Emetine is concentrated in the liver where it persists for a month after a single dose. It is slowly metabolized and excreted and can accumulate. Its ty2 is 5 days. The use of these ipecac alkaloids is limited by their toxicities. Dehydroemetine is probably less toxic than emetine. Close clinical observation is necessary when these drugs are used. Among the untoward effects are pain at the site of injection, transient nausea, cardiotoxicity (e.g., arrhythmias, congestive heart failure), neuromuscular weakness, dizziness, and rashes. [Pg.359]

For the next few pages Ipecac alkaloids, f Alangium alkaloids, New structure, Revised or established structure, II Newly isolated structure. [Pg.2]

In the early investigations discussed in Chapter 3 of Volume XIII (3), the ipecac alkaloid protoemetine (11) was synthesized (23,24) both in its racemic and natural (—) form by diisobutylaluminum hydride reduction of the... [Pg.5]

The compelling interest in the chemistry and biological activities of the ipecac alkaloids and their congeners and the attempts to synthesize related compounds have greatly multiplied the number of known benzo[a]quinoli-zine derivatives. [Pg.22]

One of the highlights covered in the last review on the ipecac alkaloids (3) was the discovery of the active amebicide ( )-2,3-dehydroemetine (136) by Brossi and co-workers (63), and its synthesis (63,130-132) and amebicidal... [Pg.23]

Analytical Methods for Identification and Determination of Ipecac Alkaloids and Related Compounds... [Pg.26]

See other pages where Alkaloids ipecac is mentioned: [Pg.242]    [Pg.244]    [Pg.415]    [Pg.21]    [Pg.351]    [Pg.386]    [Pg.378]    [Pg.379]    [Pg.312]    [Pg.314]    [Pg.267]    [Pg.1]    [Pg.1]    [Pg.2]    [Pg.3]    [Pg.4]    [Pg.5]    [Pg.5]    [Pg.7]    [Pg.9]    [Pg.11]    [Pg.13]    [Pg.15]    [Pg.17]    [Pg.19]    [Pg.21]    [Pg.21]    [Pg.23]    [Pg.25]    [Pg.26]    [Pg.26]   
See also in sourсe #XX -- [ Pg.3 , Pg.7 , Pg.13 , Pg.22 , Pg.189 , Pg.363 ]

See also in sourсe #XX -- [ Pg.3 , Pg.7 , Pg.13 , Pg.22 , Pg.189 ]

See also in sourсe #XX -- [ Pg.288 , Pg.290 ]

See also in sourсe #XX -- [ Pg.226 ]

See also in sourсe #XX -- [ Pg.610 , Pg.611 , Pg.652 ]

See also in sourсe #XX -- [ Pg.141 ]

See also in sourсe #XX -- [ Pg.135 , Pg.140 ]



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