Side Actions

There was thus obtained a mixture of Veratrum viride alkaloids having substantial utility as a hypertension reducing agent, without the concomitant marked side-actions normally associated with the clinical use of Veratrum viride extracts. This material may be clinically administered in this form, or further purification may be performed as described hereinafter. 

Number of cavities, layout and size of cavities/runners/gates/cooling lines/side actions/knockout pins/etc. Relate layout to maximize proper performance of melt and cooling flow patterns to meet part performance requirements preengineer design to minimize wear and deformation of mold (use proper steels) lay out cooling lines to meet temperature to time cooling rate of plastics (particularly crystalline types). 

As these drug (side) actions may also involve polymorphic pathways, they are also amenable to gene... 

Bolard J, et al. One-sided action of amphotericin B on cholesterol-containing membranes is determined by its self-association in the medium. Biochemistry 1991 30 5707. 

There are a few important drugs that cause nausea and vomiting as undesirable side actions when used in therapeutic dosage, and perhaps a larger number that induce the state as part of a serious toxic reaction to them in overdosage, but the number that is used intentionally to cause the patient to vomit is relatively small. Here, the following four — ipecac, apomorphine, mustard, copper sulfate — are considered as a group. 

Different actions in molds occur such as using ejector pins to remove molded parts from their cavities. Side actions of molds may be required to remove parts that have undercuts. Other actions may be required such as unscrewing threaded parts, including inserts, and so on (Chapter 17). 

Plotz M. 1936. Dinitro-ortho-cresol. A metabolic stimulator and its toxic side-actions. N Y State J Med 41 266-268. 

One may reduce concentration of atypical cells by both at the expense of selection of medical substance and by increase of doze. By this action of substance is strengthened on both atypical and normal cells that leads to effect of side action of medical treatment. 

In the gas molecule, in consequence of the one-sided action of the electric forces, the electron clouds of the two ions are of course very much deformed, so that the analysis of the ionic binding becomes extremely difficult. The circumstances are simpler in crystals, especially in the highly symmetrical ones of the rock salt (cubic face-centred, fig. 9) and similar types. In these the deformation disappears on account of the symmetry in a rock salt lattice the same force is exerted on four sides on a chlorine ion by the neighbouring sodium ions, and a similar result holds for the more distant ions. Thus... 

Ao tion. (Fire-arms.) Used gener y, in reference to the position or some characteristic of the firing mechanism as side action, snap action, etc. 

Side Actum Lock.—In Fig. 45 is shown another form of lock, commonly called a side action. The mechanism and arrangement is similar to the full bar. but it has a shoulder that fits up to the barrel If the gun be fitted with a plug or cylinder a suit able half round recess is cut in ibis shoulder to receive the ping. 

Catalepsy and Parkinsonism have been reported as side actions and the parasympathetic concomitants of these conditions are more marked than they are with phenothiazine therapy. Reserpine, like chlorpromazine, inhibits sham rage reactions, makes aggressive animals more tractable and inhibits conditioned avoidance responses . 

A model membrane system that also shows reproducible and clear 1/f behavior was described by Bezrukov and Brutyan (76). Fluctuations of current through lipid bilayers with one-sided application of three different polyene antibiotics of very close chemical structure (i.e., amphotericin B, nystatin, and mycoheptin) were studied. For one-sided application these antibiotics form channels that are weakly bound to the membrane as compared with the channels of the two-sided action. All three compounds produced pronounced noise component with spectral distribution of 1/f type (Figure 8). It was found that the noise intensity scales as the ratio of single channel conductances for amphotericin B, nystatin, and mycoheptin namely, hA hN hM = 10 5 1. For mycoheptin the spectrum is described by the function 1/f0-86 over the whole frequency range used. With two-sided application of these antibiotics, channels are more stable and strongly bound to the bilayer. In this case, significantly lower noise intensities were found the spectrum for amphotericin B was described by a single Lorentzian spectrum of relatively small amplitude (63). 

Many kinds of antitumor agents and their lead compounds have been isolated from natural resources and the medicinal sciences have made rapid progress in the treatment of carcinogenesis, but cancer currently remains a tragic disease and is one of the major causes of death in the world. Furthermore, the perfect effective antitumor agents free from side-actions have not been found out yet, and these side-actions are serious and critical problem on the treatment of cancer. Therefore, the advancement of cancer chemoprevention is very important as well as the development of cancer treatment [1,2]. 

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