Vincent, Thomas

This article is dedicated to the memory of Vincent G. Dethier. I thank Drs. Thomas A. Christensen and Leslie P. Tolbert for helpful comments on the manuscript and my many present and former coworkers and collaborators, who contributed to the work from my laboratory reviewed in this paper. Our research in this area has been supported by grants from the National Institutes of Health, National Science Foundation, and the Department of Agriculture and is currently supported by National Institutes of Health Grants AI-23253, NS-28495, and DC-00348. 

The first attempts to interpret Werner s views on an electronic basis were made in 1923 by Nevil Vincent Sidgwick (1873—1952) and Thomas Martin Lowry (1874—1936).103 Sidgwick s initial concern was to explain Werner s coordination number in terms of the sizes of the sub-groups of electrons in the Bohr atom.104 He soon developed the attempt to systematize coordination numbers into his concept of the effective atomic number (EAN).105 He considered ligands to be Lewis bases which donated electrons (usually one pair per ligand) to the metal ion, which thus behaves as a Lewis acid. Ions tend to add electrons by this process until the EAN (the sum of the electrons on the metal ion plus the electrons donated by the ligand) of the next noble gas is achieved. Today the EAN rule is of little theoretical importance. Although a number of elements obey it, there are many important stable exceptions. Nevertheless, it is extremely useful as a predictive rule in one area of coordination chemistry, that of metal carbonyls and nitrosyls. 

The authors would like to thank Vincent Bobin for the solubility data for Compound A. The authors would also like to thank the following individuals for their work on Compound B described in this chapter Daniel Gierer for manufacture of the placebo tablets Amy Orce for her work on the extraneous syringe peak Thomas Sharp, George Horan, and Ronald Morris for their work on impurity identification and Cheryl Kirkman, Heidi O Donnell, Britt-Marie Otano, Doreathea Roberts, J. Sean Space, and Gregory Steeno for their work on the small volume dissolution method. In addition, the authors would like to thank Amanda Deal and Kelly Field for their work on the HPLC purity method development for the fixed combination tablet. 

Vincent J. Kelley, Sr. VP-Eng Stacy L. Fox, General Counsel/Sr. VP Bruce G. Fischer, Sr. VP-Strategy Portfolio Thomas Golembeski, Contact-Corp. Comm. 

Kolasa, Kimberly A., 431 Lippard, Stephen J., 61 Lowery, Michael D., 121 Maroney, Michael J., 21 Mei, Rui, 219 Mirza, Shaukat A., 21 Morrow, Janet R., 431 Mukerjee, Subhasish, 83 Murphy, Catherine J., 449 Murthy, Narasimha N., 165 Neyhart, Gregory A., 405 Onuchic, Jose Nelson, 471 Pecoraro, Vincent L., 265 Penner-Hahn, James E., 219 Pressler, Michelle A., 21 Riggs-Gelasco, Pamela J., 219 Root, David E., 121 Shin, Paul K., 303 Solomon, Edward I., 121 Sono, Masanori, 351 Stassinopoulus, Adonis, 83 Thorp, H. Holden, 1, 405 Tolman, William B., 195 Turro, Nicholas J., 449 Welch, Thomas W., 405 Whitehead, Joyce P., 21 Winkler, Jay R., 471 Zovinka, Edward P., 373... 

In 1923, Nevil Vincent Sidgwick (1873-1952) and Thomas Martin Dowry (1874-1936) made the first attempts to interpret Werner s views on an electronic basis. Sidgwick tried to... 

Smith, Keith Vincent. The Illustrated Earth Garden Herbal, a herbal companion, Thomas Nelson Australia Pty Ltd. 

Thompson, K.F. 1972. Cytoplasmic male sterility in oilseed rape. Heredity 29 253-257. Thomas, P. 1992. Canola Growers Manual. Winnipeg, Canada Canola Council of Canada. Vincent, M.R.L. 2008. Genetic diversity and its relationship to hybrid performance in high eructic acid rapeseed. M. Sc. Theseis. University of Manitoba, Winnipeg, Manitoba, Canada. 

Thomas W. Bell, Dankl L. BecUes, Peter J. Cragg, Jia Ud, James Maioriello, Andrew T. Papou, and Vincent J. Santora... 

Thomas SN, Cripps D, Yang AJ (2009) Proteomic analysis of protein phosphorylation and ubiquitination in Alzheimer s disease. Methods Mol Biol 566 109-121 Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, lUes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O-Symbol-Rourke JG, Khashwji H et al (2009) IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol 21 Dec 2009 [Epub ahead of print]... 

Tables 4.1 and 4.2 summarize the main types of studies of errors and adverse events, and their respective advantages and limitations. Thomas and Petersen s original source version has been separated into two separate tables and the content has been adjusted in particular, a section on case analysis has been added. Case analyses, usually referred to as root cause analysis or systems analysis, share some of the features of morbidity and mortality meetings, but are generally more focused and follow a particular method of analysis (Vincent, 2003) (Chapter 8).

Thomas, B.J. and Brennan, T. (2001) Errors and adverse events in medidne an overview, in Clinical Risk Management. Enhancing Patient Safety, 2nd edn (ed. C.A. Vincent), BMJ Publications, London, pp. 31-44. 

Arthur J. Stipanovic, Thomas E. Amidon, Gary M. Scott, Vincent Barber, and Misty K. Blowers ... 

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