Vancocin - Vancomycin

Vancide 89RE Vancide TH Vancide 51Z Vancocin Vancomycin... [Pg.1047]

Only three dalbaheptides are commercialized vancomycin (39) and teicoplanin (18—22) for human health, and avoparcin (63—65) for animal usage. Vancomycin, the main trademark of which is EH Lilly s Vancocin had 1990 sales around 160 million. Total annual production is in the vicinity of 8 t. Teicoplanin, trademarked Targocid, had 1990 sales of 35 million corresponding to 200 kg. Teicoplanin is commercialized in Europe, Hong Kong, Korea, and the Middle East. It is at the late developmental clinical phase in North America and Japan. Avoparcin is used as a growth promoting feed additive (see... [Pg.537]

Vancomycin (Vancocin) acts against susceptible gram-positive bacteria by inhibiting bacterial cell wall synthesis and increasing cell wall permeability. This drug is used in the treatment of serious gram-positive infections that do not respond to treatment with other anti-infectives. It also may be used in treating anti-infective-associated pseudomembranous colitis caused by Clostridium difficile. [Pg.103]

Vancocine (Lilly) Vancomycine Dakota Pharm (Dakota) Vancomycine Lederle (Wyeth-Lederle)... [Pg.2159]

For each structural class of antibacterial discussed, there are many members in chnical use. I have selected a few as representative examples of each class. There are several additional classes of antibacterials as well. Notable is vancomycin (Vancocin), like the p-lactam antibacterials an inhibitor of cell wall biosynthesis although the site... [Pg.327]

Trimethoprim (TMP)-Sulfamethoxazole (SMX) [Co-Trimoxa-zole] (Bactrim, Septra) Vancomycin (Vancocin, Vancoled)... [Pg.36]

Vancomycin (Vancocin) is a complex tricyclic glycopep-tide antibiotic produced by Streptomyces orientalis, while teicoplanin (Targocid) is derived from Actino-planes (Actinomyces) teichomyceticus. Teicoplanin has two major components a phosphoglycolipid (Aj) and five chlorine-containing glycopeptides (A2). It is available as an investigational drug. [Pg.553]

Vancocin HC1 for oral solution contains vancomycin hydrochloride equivalent to 10 g (6.7 mmol) or 1 g (0.67 mmol) vancomycin. Calcium disodium edetate, equivalent... [Pg.205]

D AB-Vancomycin (Astrapin) F Vancocine (Lilly) I Vancocina (Lilly)... [Pg.2159]

Valrelease, 526 Vamidothion, 85 Van Deemter plots, 191 Van Urk reagent, 1171 Vancenase, 374 Vanceril, 374 Vancocin, 1060 Vancomycin, 1060 Vancomycin hydrochloride, 1060 Vandid, 593... [Pg.1653]

Vancomycin (Vancocin) Protein-Binding 10% Half-Life 5-11 hours IV 500 mg Every 6 hours... [Pg.158]

Vancomycin (Vancocin) SorP (Hep or EDTA) Therap pg/mL 0.690 pmol/L... [Pg.2315]

THERAPEUTIC USES Vancomycin (vancocin, others) is marketed for intravenous use as a sterile powder. It should be diluted and infused over at least 60 minutes to avoid infusion-related adverse reactions. The usual dose of vancomycin for adults is 30 mg/kg/day in 2-3 divided doses. A trough serum concentration of 5-15 (Xg/mL (10-20 (Xg/mL for serious infections such as endocarditis or meningitis) is recommended. Doses above 30 mg/kg/day may be required to achieve these trough concentrations, and up to 60 mg/kg/day has been suggested for meningitis. The peak concentration is not monitored routinely but should generally remain below 60 (Xg/mL to avoid ototoxicity. [Pg.775]

Vancomycin (Vancocin) Prevents transfer of cell wall precurser from plasma membrane to cell wall. DOC Antibiotic associated colitis (C. d/ff/c//e). Staph and Strep infections which are resistant to penicillin or methacillin. Thrombophlebitis, ototoxicity, nephrotoxicity. When administered by rapid IV tachycardia, flushing, paresthesias, hypotension, severe nephrotoxicity... [Pg.102]

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