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Uterus, innervation

Ritodrine has an effect on beta (p)2-adrenergic receptors, principally those that innervate the uterus. Stimulation of these p2-adrenergic receptors inhibits uterine smooth muscle contractions. The pradrenergic receptors are located in the heart and are not stimulated by ritodrine when administered as prescribed. Ritodrine is used to... [Pg.563]

N-methylscopolamine (Costa et al. 1982b Schwab et al. 1983). Animals made tolerant to disulfoton were resistant to the lethal or adverse effects of cholinergic agonists, such as carbachol (Brodeur and DuBois 1964 Costa et al. 1981 Schwab and Murphy 1981) and oxotremorine (Costa et al. 1982b McPhillips 1969a), which are not hydrolyzed by acetylcholinesterase. Tissues from animals tolerant to disulfoton such as the ilea (Foley and McPhillips 1973 McPhillips 1969b McPhillips and Dar 1967) and the atria (Perrine and McPhillips 1970 Schwab et al. 1983), were resistant to the effects of carbachol and/or oxotremorine. Because the uterus and vas deferens have a relatively sparse parasympathetic innervation compared to the ileum and do not receive a steady flow of impulses via this system, these tissues were not as subsensitive to carbachol as the ileum (Foley and McPhillips 1973). Thus, acetylcholine accumulation may be a prerequisite for tolerance development. [Pg.99]

Q9 Myometrial contractile activity is modified by both endocrine and autonomic factors. The increase in oestrogens during pregnancy gradually increases both the excitability of uterine smooth muscle and its sensitivity to agonists, particularly oxytocin. The uterus receives sympathetic innervation, which exerts excitatory effects via alpha-1-receptors (a i-receptors). Uterine smooth muscle also possesses beta-2-receptors (/d2-recept°rs)> which mediate relaxation. [Pg.314]

The nervous system (Fig. 1) consists of the central nervous system (CNS with brain and spinal cord) and the peripheral system (with afferent sensory and efferent motor nerves), which regulate all aspects of bodily function and is staggering in its complexicity. Another distinction is between the somatic (sensoric system, innervation of skeletal muscles) and the autonomic nervous system (heart and blood circulation respiration motility of the gastrointestinal tract, smooth muscles of gall and urinary bladder, ureter, uterus, secretion of glands). The autonomic nervous system is further divided into a sympathetic and... [Pg.5]

Berberine is said to resemble hydrastine and hydrastinine in augmenting the tonus and contractions of the uterus both in situ and excised (147). Chopra and his associates observed these effects on the isolated cat uterus with concentrations of 1 100,000 and in situ, following doses of 2.0-4.0 mg./kg. The effects were thought to be due chiefly to an action on effector cells innervated by cholinergic nerves, since they were abolished by atropinization (148). The rat uterus appears to respond in a different manner. According to Gibbs, berberine produces a slow diminution of tonus, amplitude, rate of contraction, and diminished response to acetylcholine. In the presence of berberine, hydrastine causes a powerful reversal of the tonic action of acetylcholine (149). [Pg.186]

Veratrine is best known for its cardiovascular actions, but it exerts a stimulant action on the rabbit uterus in situ and excised, in very small doses (270, 271). According to Kunisho, the action on the isolated uterus is a direct one on the smooth muscle. In vivo, the action is said to involve both the central nervous system and the sympathetic innervation of the uterus. The effect of a dose of 0.001 mg./kg. is completely abolished by yohimbine,... [Pg.200]


See other pages where Uterus, innervation is mentioned: [Pg.48]    [Pg.28]    [Pg.374]    [Pg.348]    [Pg.164]    [Pg.172]    [Pg.173]    [Pg.184]    [Pg.185]    [Pg.187]    [Pg.191]    [Pg.191]    [Pg.192]    [Pg.192]    [Pg.202]    [Pg.35]    [Pg.575]    [Pg.35]    [Pg.653]   
See also in sourсe #XX -- [ Pg.33 ]

See also in sourсe #XX -- [ Pg.33 ]

See also in sourсe #XX -- [ Pg.33 ]




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Innervation

Uterus

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