Urokinase-type plasminogen activator uPAR

D10. Dumler, I. T., Petri, T., and Schleuning, W. D., Interaction of urokinase-type plasminogen activator (uPA) with its cellular receptor (uPAR) induces phosphorylation on tyrosine of a 38 kDa protein. FEBS Lett. 322, 37-40 (1993). [Pg.160]

Plesner T, Behrendt N, Ploug M. Structure, function and expression on blood and bone marrow cells of the urokinase-type plasminogen activator receptor, uPAR. Stem Cells 1997 15(6) 398-408. [Pg.95]

Urokinase-Type Plasminogen Activator Receptors (uPAR). 139... [Pg.101]

Reuning U, Sperl S, Kopitz C, et al. Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) development of antagonists of uPA/uPAR interaction and their effects in vitro and in vivo. Curr Pharm Des 2003 9 1529-43. [Pg.792]

Serrati S, Margheri F, Fibbi G, et al. (2008) Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type plasminogen activator receptor (uPAR, CD87) expression. J Pathol 214 545-554... [Pg.60]

Urokinase-type plasminogen activator (EC 3.4.21.73) is synthesised in a single-chain form and is converted to an active, two chain form after it binds to its cell surface receptor, uPAR. Treatment human of alveolar type II cells (A549) with 1 to 5 jUM chromium(Vl) for 4 and 12 h decreased both the specific activity and the amount of uPA protein (Shumilla and Barchowsky 1999). Chromium reduced uPA protein levels by inhibiting protein synthesis and had no effect on uPA mRNA levels or the rate of uPA protein degradation. In contrast, both mRNA and protein levels for the uPA receptor were increased by treatment with concentrations of chromium(VI) that did not completely inhibit protein synthesis. [Pg.206]

Unpredictability, 238, 244 Unsaturated fatty acids, 2471 uPA. See Urokinase-type plasminogen activator (uPA) uPAR, 2201 UPLC-qToF/MS, 1026 UPLC-TOFMS, 3360... [Pg.4240]

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