Urea nitro

Figure 5.27 Synthon energy calculations in Spartan (RHF/6-31C ) on the urea-- urea homodimer and urea- - -nitro and urea- --DMF heterodimers in model compounds...

Amine B.P. M.P. Aceta- mide Benz- amlde Benzene- SUlphOD- amlde p-Tolu- enesul- phoD- amlde Benzal Derivative Picrate 3-Nitro- phthal- imide 2 4-Dinitro-phenyl Derivative Formyl Derivative Phenyl thio- urea... 

Certain features of the addition of acetyl nitrate to olefins in acetic anhydride may be relevant to the mechanism of aromatic nitration by this reagent. The rapid reaction results in predominantly cw-addition to yield a mixture of the y -nitro-acetate and y5-nitro-nitrate. The reaction was facilitated by the addition of sulphuric acid, in which case the 3rield of / -nitro-nitrate was reduced, whereas the addition of sodium nitrate favoured the formation of this compound over that of the acetate. As already mentioned ( 5.3. i), a solution of nitric acid (c. i 6 mol 1 ) in acetic anhydride prepared at — 10 °C would yield 95-97 % of the nitric acid by precipitation with urea, whereas from a similar solution prepared at 20-25 °C and cooled rapidly to —10 °C only 30% of the acid could be recovered. The difference between these values was attributed to the formation of acetyl nitrate. A solution prepared at room... 

Polymers. AH nitro alcohols are sources of formaldehyde for cross-linking in polymers of urea, melamine, phenols, resorcinol, etc (see Amino RESINS AND PLASTICS). Nitrodiols and 2-hydroxymethyl-2-nitro-l,3-propanediol can be used as polyols to form polyester or polyurethane products (see Polyesters Urethane polymers). 2-Methyl-2-nitro-l-propanol is used in tires to promote the adhesion of mbber to tire cord (qv). Nitro alcohols are used as hardening agents in photographic processes, and 2-hydroxymethyl-2-nitro-l,3-propanediol is a cross-linking agent for starch adhesives, polyamides, urea resins, or wool, and in tanning operations (17—25). Wrinkle-resistant fabric with reduced free formaldehyde content is obtained by treatment with... 

Obsolete uses of urea peroxohydrate, as a convenient source of aqueous hydrogen peroxide, include the chemical deburring of metals, as a topical disinfectant and mouth wash, and as a hairdresser s bleach. In the 1990s the compound has been studied as a laboratory oxidant in organic chemistry (99,100). It effects epoxidation, the Baeyer-Villiger reaction, oxidation of aromatic amines to nitro compounds, and the conversion of sodium and nitrogen compounds to S—O and N—O compounds. 

Nitration of aromatic amines with urea nitrate in sulfuric acid is reported to yield the -nitro derivative exclusively (44). When the para position is blocked, the meta product is obtained in excellent yield. 

In a synthesis of minocycline, interesting use was made of a reductive alkylation of a nitro function, accompanied by loss of a diazonium group. The sequence provides a clever way of utilizing the unwanted 9-nitro isomer that arises from nitration of 6-demethyl-6-deoxytetracycline (//). When di-azotization was complete, urea and 40% aqueous formaldehyde were added, and the entire solution was mixed with 10% palladium-on-carbon and reduced under hydrogen. No further use of this combined reaction seems to have been made. 

Urea maybe reacted with acetoacetic ester and that product nitrated to give 5-nitro-orotec acid That is hydrogenated, then reacted with urea and potassium cyanate to give tetrahydroxypy-imidopyrimidine. The tetrahydroxy compound Is converted to the tetrachloro compound POCI3. Reaction with diethanolamine and then with piperidine gives dipyridamole. 

Eight isomers are in the literature 1 -A zido-2-nitronaphthalene (2-Nitro-l-naphthyl azide). Long yel needles from aq acet, mp 103—4° with decompn (Refs 1 4) CA Registry No 16714-21-9. Prepd by the action of Na azide on 2-nitro-1-naphthalenediazonium sulfate with urea in glac acet ac (Ref 4). It decomps at 150° with N evolution, and in toluene at 110° to give a 90% yield of... 

Uses. Since 1947, 70 to 85% of the annual USA production of nitric acid has gone into the production of NH4 nitrate fertilizer, initially in the form of solid prills currently, increasing amounts have been supplied mixed with excess ammonia and/or urea as aqueous nitrogen solution for direct application to the soil. Some 15% is used in explsj (nitrates nitro compds), and about 10% is consumed by the chemical industry. As the red fuming acid or as nitrogen tetroxide, nitric acid is used extensively as the oxidizer in proplnts for rocketry. It is estimated that current USA capacity for nitric acid is in excess of 10 million tons (Refs 30, 34, 36 37)... 

The Post Nitrated Poly urea Polymer of 3-Nitro-3-Aza-1,5-Pentane Diisocyanate and Water. 

C7H 4C1N 54777-54-7) see Clemastine 2-chloroethyl 4-nitrophenyl ether (C HgClN03 3383-72-0) see Dofetilide 7V-(2-chloroethyl)-N -(5-nitro-2-thiazolyl)urea (CgH7ClN403S 3311-98-6) see Niridazole 7V-(2-chloroethyl)piperidine... 

Chorionic gonadotropin. Follicle stimulating hormone Urea, Uric add. Bilirubin, Cortisol, n-Maimitol. n-Glucose, Sodium pyruvate, 4-hydroxy-3-methoxy mandelic add, 4-Nitro-phenol, 17 Amino adds in HQ, Angiotensin-I, Tripahnitin, Bone meal (8 elements), Bone ash (8 elements), lithium carbonate Luteinizing hormone. Thyroid stimulating hormone... 

Nitro-3(2,4-dinitrophenyl) urea Nitroguanidine N-Nitromethylamine Nitrourea... 

Cone, aqueous solutions of the urea salt will dissolve sohd or liquid aromatic nitro compounds (e g. picric acid [1], or nitrobenzene [2]) to give high velocity explosives. See next item below... 

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