Thiazolyl urea

The reaction of 2-amino-5-nitrothiazole with (3-chloroethyl isocyanate gives the corresponding thiazolyl urea (137) (Scheme 90) (298). Other examples are given in Section V.l.B, where the preparation of thiazolyl-thioureas is discussed,... 

Characteristic spectroscopic data (infrared and NMR) of 2-thiazolyl ureas are given in a recent report (484). Their characteristic ultraviolet absorption is in the 260 to 270 nm region (487). 

Alkylation of bis(4-methyl-2-thiazolyl)urea (257) with dimethyl sulfate gives product 258 dimethylated on the ring nitrogens (Scheme 154) (488). Alkylation of l-alkyl-3-(2-thiazolyl)urea from its derived anion formed by NaH gives 259 (Scheme 155). 

C7H 4C1N 54777-54-7) see Clemastine 2-chloroethyl 4-nitrophenyl ether (C HgClN03 3383-72-0) see Dofetilide 7V-(2-chloroethyl)-N -(5-nitro-2-thiazolyl)urea (CgH7ClN403S 3311-98-6) see Niridazole 7V-(2-chloroethyl)piperidine... 

Isocyanate, Me, 431 phenyl, 431 Isocyanates, 58 acyl isocyanates, 92 alkyl isocyanates, 92, 118 aryl versus alkyl, 118 with hydrazinothiazoles, 100, 106 with 2-imino-4-thiazolines, 125 to mesoionic compounds, 65 to thiazolyl urea, 58, 92 Isoindolenine derivative, 56 Isomerism, E-Z equilibrium, 23 Isomerization, catalyst in aji-unsaturated acids, 438... 

Ullmann synthesis, ] 15 Unsaturated acid chlorides, acylation, 49 Uranium derivatives, 154 Uranyl ions, 108 Urea, with azothiazoles. 111 to thiazolyl urea, 56 see also Thiazolyl urea Urine, 2-aminothiazoles in, 85 metabolite in, 85... 

SYNS N-ETHYL-N -(5-NITRO-2-THIAZOLYL)UREA HEPZIDE NCI-C03792 NITHIAZID NITHIAZIDE... 

ETHYL-l-NITROSOUREA see ENVOOO N-ETHYL-N-NITROSO-UREA see ENVOOO ETHYL NITROSOURETHAN see NKE500 N-ETHYL-N-NITROSOURETHAN see NKE500 ETHYL NITROSOURETHANE see NKE500 N-ETHYL-N-NITROSOURETHANE see NKE500 N-ETHYL-N-NITROSOVINYLAMINE see NKFOOO l-ETHYL-3-(5-NTTRO-2-THIAZOLYL) UREA see ENV500... 

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