Uranium compounds uranyl nitrate

In addition, the sequestration patterns of the different uranium compounds are important determinants for the target organ chemical and radiological toxicities of these compounds. The site of deposition for the soluble uranium compounds (uranyl nitrate, uranium tetrachloride, uranium hexafluoride) is the bone, while the insoluble compounds (uranium hexafluoride, uranium dioxide) accumulate in the lungs and lymph nodes (Stokinger 1953). 

The main site of long-term retention for soluble uranium compounds (uranyl nitrate, uranium tetrachloride, uranium dioxide) is the bone, while the inhaled insoluble compounds (uranium... 

Other uranium compounds. Uranyl nitrate. A phase diagram for the. sy.stem uranyl nitrate-water [12] is shown in Fig. 3-10. Altliough uranyl nitrate remains very soluble at the elevated temperatures of interest for power-reactor operation, the nitrate group in such solutions decomposes to yield oxides of nitrogen which appear in the vapor phase. Although this situation is reversible witli the lowering of temperature, it docs introduce corrosion problems with respect to the apor pliase. The... 

Electron microscopy and X-ray microanalytical methods showed that uranium as uranyl nitrate hexahydrate penetrated the stratum corneum within 15 minutes and accumulated in the intracellular space between the viable epidermis and the stratum corneum (De Rey et al. 1983). As is the case with inhalation and oral absorption, water solubility is an important determinant of absorption, and no penetration was observed with the insoluble compounds uranium dioxide, uranyl acetate, or ammonium diuranate. After 48 hours, uranium applied as uranyl nitrate was no longer found in the skin and toxicity developed, indicating that the uranium had been absorbed into the blood. 

One site of deposition for the soluble compounds (uranyl nitrate, uranium tetrachloride, uranium hexafluoride) in animals was the skeleton, but accumulation was not seen in bone at levels below 0.25 mg U/m over a period of 2 years in rats exposed to soluble compounds (uranyl nitrate, uranium tetrachloride, uranium hexafluoride) in one study. The insoluble compounds (uranium hexafluoride, uranium dioxide) were found to accumulate in the lungs and lymph nodes after the inhalation exposure. For uranyl nitrate exposure, no retention was found in the soft tissues. Accumulation of uranium was also found in the skeleton (Stokinger 1953). The amount distributed in the skeleton has been reported to be 23 5% of the intake in dogs (Morrow et al. 1972) 28-78% in rats (Leach et al. 1984) and 34-43% in guinea pigs (Leach et al. 1984). A biological half-time of 150-200 days (Ballou et al. 1986) or 70 days (Morrow et al. 1982) in the skeleton has been reported following inhalation exposure to soluble uranium compounds (e.g., uranium hexafluoride). 

For Type M, about 70% of the deposit in AI reaches the blood eventually. There is rapid absorption of about 10% of the deposit in BB and bb, and 5% of material deposited in ET2. Thus, there is rapid absorption of approximately 2.5% of the deposit in ET for nose breathing, and 5% for mouth breathing. Type M compounds include unpure uranium trioxide, uranyl nitrate (which can behave as Type F), ammonium diuranate, uranium oxtaoxide (which can behave as Type S), and uranium tetrafluoride (which can behave as Type F). 

Ingested uranium is excreted mostly in the feces urinary excretion is generally low. The biological halftimes of soluble uranium compounds (uranium hexafluoride, uranyl fluoride, uranium tetrachloride, uranyl nitrate hexahydrate) are estimated in days or weeks those of the less soluble compounds (uranium tetrafluoride, uranium dioxide, triuranium octaoxide) are estimated in years. No information is currently available on the excretion of dermally absorbed uranium. Transdermally absorbed uranium is expected to behave identically to uranium compounds absorbed through the lungs and the gastrointestinal tract. 

URANIUM. SOLUBLE COMPOUNDS (ASU) u Synonyms vary depending upon specific compound Uranyl nitrates combustibles. Uranium hexa-nuoride water Properties vary depending upon specific compound ... 

Several uranium compounds tested on the eyes of animals caused severe eye damage as well as systemic poisoning. The anion and its hydrolysis products determine the degree of injury. A hot nitric acid solution of uranyl nitrate spilled on the skin caused skin burns, nephritis, and heavy metal encephalopathy. Prolonged skin contact with uranium com-... 

Uranyl nitrate is obtained as an intermediate in recovering uranium from its minerals. The compound can be prepared by reacting triuranium octaoxide, UsOs, with nitric acid. It is separated and purified by extraction with ether. 

Uranium Compounds with Lower Oxidation States. Pour 5 ml of a uranyl nitrate solution into a test tube, add 1 ml of a 10% hydrochloric acid solution, and drop one or two small pieces of zinc into the tube. How can the change in the solution s colour be explained Pour the solution into three test tubes. Pour a potassium permanganate solution dropwise into one tube. What happens What properties do uranium(lV) compounds have ... 

In animal studies, soluble uranium compounds have been shown to penetrate the skin of rats within 15 min of application (de Rey et al, 1983). The penetration was as high as 7 g/kg body weight for ammonium uranyl tricarbonate while uranyl nitrate hexahydrate ranged from 0.5 to 7 g/kg body... 

No treatment-related renal effects were seen in other studies when animals were exposed to uranium compounds by inhalation at concentrations as high as 10 mg U/m (as uranium dioxide) in guinea pigs for 28 weeks, 2 mg U/m (as uranyl nitrate hexahydrate) in guinea pigs for 26 weeks, and 16 mg U/m (as uranyl nitrate hexahydrate) in rats for 4 weeks (Rothstein 1949c Stokinger et al. 1953). 

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