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Uracil, uridine

Uracil, uridine and uridine nucleotides. Resolved by ion-exchange chromatography AGl (Cl form). [Lindsay et al. Anal Biochem 24 506 7968.]... [Pg.572]

This reaction has also been shown to occur in cytidine, cytidylic acid, uracil, uridine, and uridylic acid (found in RNA) but reportedly not in thymine, thymidine, or thymidylic acid/55 The photohydration has been found to be partially reversible, dehydration being nearly complete at extremes of temperature and pH. [Pg.590]

Uracil Uridine Uridylic acid Uridine monophosphate (UMP) Uridine diphosphate (UDP) Uridine triphosphate (UTP)... [Pg.6]

U UDP UDPGA dUMP UdRP Uracil Uridine diphosphate Uridine diphosphate glucuronic acid Deoxyuridylate-5 -monophosphate Deoxyuridylic acid... [Pg.303]

Uracil, uridine, and uridine 5-phosphate cannot substitute for uridine 5-triphosphoric acid in this reaction. When ammonia was replaced by hy-... [Pg.230]

Figure 11.6 Separation of zebularine (last peak) and metabolites with HILIC [reproduced with permission from J.H. Beumer et al., J. Chromatogr. fl, 831,147 (2006)]. Conditions sample, mouse plasma after sample preparation column, 25cm X 4.6mm i.d. stationary phase, Zorbax NH2, 5 J,m mobile phase, 0.6ml min isopropanol (gradient 12—49%)—1 M ammonium formiate (0.24-1.0%)-acetonitrile (88-50%) radioactivity detector. The analytes are labelled with radioactive C at the positions with asterisks. Elution order zidovudine (internal standard), dihydrouracil, uracil, uridine (these three compounds are metabolites), and zebularine (drug). Figure 11.6 Separation of zebularine (last peak) and metabolites with HILIC [reproduced with permission from J.H. Beumer et al., J. Chromatogr. fl, 831,147 (2006)]. Conditions sample, mouse plasma after sample preparation column, 25cm X 4.6mm i.d. stationary phase, Zorbax NH2, 5 J,m mobile phase, 0.6ml min isopropanol (gradient 12—49%)—1 M ammonium formiate (0.24-1.0%)-acetonitrile (88-50%) radioactivity detector. The analytes are labelled with radioactive C at the positions with asterisks. Elution order zidovudine (internal standard), dihydrouracil, uracil, uridine (these three compounds are metabolites), and zebularine (drug).
Uracil, uridine and uridine nucleotides. These are resolved by ion-exchange chromatography with... [Pg.703]

ULSI UMP uncor uns UPS ur Ura Urd URL USDA USP USP UTP UV UV PES UV-vis V ultra-large-scale integration uridine 5,-monophosphate, uridine 5,-phosphati uncorrected unsymmetrical ultraviolet photoelectron spectroscopy urea (ligand) uracil uridine uniform resource locator U.S. Department of Agriculture United States Pharmacopeial Convention The United States Pharmacopeia uridine 5,-triphosphate ultraviolet ultraviolet photoelectron spectroscopy ultraviolet—visible... [Pg.309]

There are five dihydropyrimidines. The 1,4- and the 1,6-dihydropyrimidines can readily interconvert by tautomerism because of the mobile NH proton. The common metals to effect hydrogenation can be used . Platinum has been the catalyst of choice for the reduction of the 5,6-double bond of uracils, for example, in the addition of deuterium to uracil to produce [5,6- H2]5,6-dihydrouracil. But in the reduction of 2(l/f)-pyrimidinone and its iV-methyl derivative it is the 1,6-dihydro derivatives which are formed. The addition of hydrogen to the 5,6-bond of thymidine and other 5-substituted uridines is stereospecific with rhodium-on-alumina as catalyst. Rhodium-on-charcoal has been useful for hydrogenation of the 5,6-double bond in uracils, uridine, and isocytosine. Raney nickel readily promotes saturation of the 5,6-double bond. Thio derivatives may either be dethiated or taken further to reduced forms by Raney nickel catalysts . [Pg.163]

Uridine is a nucleoside containing uracil. Uridine differs from uracil in containing a sugar (ribose). Phosphorylation of uridine produces a nucleotide found in RNA. [Pg.733]

Thymine Uracil Uridine Thymidine Uridine 5 -phosphate Thymidine 5 -phosphate... [Pg.1109]

Nucleosides, Nucleotides, Derivatives, and Related Compounds. — 5-Dimethyl-aminouridine, 5-methylaminomethyl-2-thiouridine, 2, 3 -O-isopropylidene-5-methylaminomethyl-2-thiouridine, 2 -deoxy-5-isopropyluridine, 5-amino-2, 5 -dideoxy-5-iodouridine, 5-nitro-l-( 3-D-ribofuranosyluronic acid)uracil, uridine 3 -phosphate, and uridine 5-diphosphate dipotassium salt. ... [Pg.219]

Uracil, uridine, adenine, adenosine and guanine have been identified in the roots (147). Choline was isolated from the roots as the reineckate in 0.55% yield (148) and a-pyrrolidone was identified by GLC analysis (149). [Pg.62]

T6 Tezuka, M. and Tamemasa, O. Incorporation characteristics of uracil, uridine and orotic acid into ribonucleic acid of neoplastic cells. Gann, 68, 287-292 (1977)... [Pg.107]

Rj = H Rs = NH2 Adenine Adenosine Deoxyadenosine R4 = 0H R5 = H Uracil Uridine Deoxyuridine... [Pg.462]

Trace amounts of uracil, uridine, thymine, and cytosine may also be found in human urine, along with pseudouridine, 5-methylcytosine, 3-methylcytosine, and 2 -0-methylcytidine (6, 7). Immediately following X-irradiation the urinary excretion of deoxycytidine and thymidine is markedly increased (8). [Pg.203]


See other pages where Uracil, uridine is mentioned: [Pg.52]    [Pg.445]    [Pg.313]    [Pg.193]    [Pg.206]    [Pg.288]    [Pg.93]    [Pg.518]    [Pg.303]    [Pg.535]    [Pg.63]    [Pg.1131]    [Pg.270]    [Pg.417]    [Pg.21]    [Pg.235]    [Pg.275]    [Pg.106]    [Pg.401]    [Pg.773]    [Pg.43]    [Pg.466]    [Pg.3450]    [Pg.1027]    [Pg.882]    [Pg.326]    [Pg.342]   
See also in sourсe #XX -- [ Pg.119 , Pg.585 ]




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