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Unoprostone

C30H34O5 39865-76-4) see Unoprostone isopropyl [3ait-[3aa,4a( ),5p,6aa]]-[l,l -biphenyl]-4-carboxylic acid hexahydro-2-oxo-4-(3-oxo-l-octenyl)-2i/-cyclopen-ta[A]furan-5-yl ester... [Pg.2308]

C21H20O5 31752-99-5) see Dinoprost Latanoprost Unoprostone isopropyl cortisol 21-acetate... [Pg.2338]

C 1H15NO2S 3339-36-4) see. Tiemoniuin iodide (2-oxononyl)phosphonic acid dimethyl ester (C11H23O4P 57497-25-9) see Unoprostone isopropyl (S)-4-[[4-[(2-oxo-4-oxazolidinyl)methyl]phenyl]hydrazo-no]butanenitrile... [Pg.2429]

Pharmacokinetics Peak response occurs in 4-8 wk. The duration of a single dose is about 10 hr. Hydrolyzed to unoprostone free acid form in the cornea. Rapidly eliminated from plasma. Excreted as metabolites in urine. Half-life 14 min. [Pg.1284]

Contraindications Hypersensitivity to unoprostone isopropyl, benzalkonium chloride, or any other component of the formulation... [Pg.1284]

Latanoprost, bimatoprost, travoprost, unoprostone Increased outflow Topical... [Pg.210]

Latanoprost is an analogue of PGF2 , used to treat glaucoma. The use of latanoprost and unoprostone in the treatment of open-angle glaucoma and ocular hypertension has been reviewed (1). More data on safety are needed to calculate its benefit-to-harm balance. [Pg.122]

Eisenberg DL, Camras CB. A preliminary risk-benefit assessment of latanoprost and unoprostone in open-angle glaucoma and ocular hypertension. Drug Sat 1999 20(6) 505—14. [Pg.126]

Unoprostone is a synthetic prostaglandin analogue of PGF2a used in the treatment of glaucoma. Its mechanism of action is believed to be by enhancing uveoscleral outflow, like latanoprost. [Pg.134]

The success of latanoprost has stimulated development of similar prostanoids with ocular hypotensive effects, and bimatoprost, travaprost, and unoprostone are now available. These drugs act at the FP receptor and are administered as drops into the conjunctival sac once or twice daily. Adverse effects include irreversible brown pigmentation of the iris and eyelashes, drying of the eyes, and conjunctivitis. [Pg.454]

Unoprostone (Rescula) Ophthalmic solution 0.15% Zafirleukast (Accolate) Oral 10, 20 mg tablets Zileuton (Zyflo))... [Pg.456]

See other pages where Unoprostone is mentioned: [Pg.622]    [Pg.2148]    [Pg.2148]    [Pg.2149]    [Pg.2149]    [Pg.2380]    [Pg.2391]    [Pg.2404]    [Pg.2452]    [Pg.600]    [Pg.608]    [Pg.600]    [Pg.610]    [Pg.637]    [Pg.640]    [Pg.640]    [Pg.1284]    [Pg.463]    [Pg.414]    [Pg.663]    [Pg.681]    [Pg.105]    [Pg.134]    [Pg.134]    [Pg.92]    [Pg.217]    [Pg.2148]    [Pg.2308]    [Pg.2380]    [Pg.2391]    [Pg.2429]    [Pg.2452]    [Pg.805]   
See also in sourсe #XX -- [ Pg.134 ]

See also in sourсe #XX -- [ Pg.76 ]

See also in sourсe #XX -- [ Pg.53 ]

See also in sourсe #XX -- [ Pg.1103 ]

See also in sourсe #XX -- [ Pg.1117 ]



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Prostaglandins unoprostone

Unoprostone adverse effects

Unoprostone isopropyl

Unoprostone isopropyl ester

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