Triterpenoids: biological activities

Kanokmedhakul K, Kanokmedhakul S, Phatchana R. Biological activity of anthraquinones and triterpenoids from Prismatomeris fragrans. J Ethnopharmacol 2005 100 284-288. 

Buxus alkaloids have a imique steroid-triterpenoid pregnane type skeleton with C-4 methyls, 9fl, lOp cycloartenol system with a degraded C-20 side chain [21-33]. These alkaloids exhibit varions biological activities including anti-HIV, anti-TB,... 

Several reviews concerning the structures, taxonomic distribution, evolution and biological activities of sea cucumber triterpenoid... 

Yoshiki Y, Kodon S and Okubo K (1998) Relationship between chemical structures and biological activities of triterpenoid saponins from soybean. Biosci Biotechnol Biochem 62, 2291-2199. 

Alfhough bearing a sterane nucleus, fhe biosyntheses of cucurbitacins and dammaran-type saponins will not be reviewed here. Both groups belong to the triterpenoids, the chemistry, biosynthesis and biological activities of which have been described elsewhere (Charlwood and Banthorpe, 1991 ... 

Lanost-8-en-3-one 9, as well as methyl oleanonate, afforded regioselectively the corresponding [2,3-first synthesis of a new lanostane triterpenoid 11 with a cyano enone moiety in ring A, interesting from the perspective of biological activity, was also achieved <03JOC4991>. 

During the almost 20-years of research on Astragalus sapogenins and saponins, more than 40 species firom this genus have been studied and above 40 triterpenoid sapogenins and up to 130 saponins have been isolated and identified until now, and for some of them the biological activity has also been studied. 

Structure and Biological Activity of Triterpenoids and Aromatic Compounds from Medicinal Plants... 

K. Hiller New results on the structure and biological activity of triterpenoid saponins in Biologically Active Natural Products Oxford Science Publications. (K. Hostettmann, P. Lea eds.) 12 (1987), 167. 

Woldemichael, G. and Wink, M. (2001). Identification and biological activities of triterpenoid saponins from Chenopodium quinoa. J. Agric. Food Chem. 49, 2327-2332. 

Albizzia adiantifolia (Schnmach.) W. F. Wight [ilnhlangushiyane, flat crown] (Fabaceae) stem bark infusion is used for skin problems. The stem bark contains flavonoids, glycosides, polyphenols, saponins, steroids and tamiins (75). The saponin triterpenoids are biologically active (59). 

Yoshiki Y, Kudou S, Okubo K (1998) Relationship Between Chemical Structures and Biological Activities of Triterpenoid Saponins from Soybean (Review). Biosci Biotechnol Biochem 62 2291... 

Several natural products are known to modify the sense of sweet taste. Such compounds can be either sweetness inhibitors or sweetness inducers/enhancers. A review of Suttisri et al., 1995 summarizes data on phytochemistry and biological activity of more than 40 triterpenoid sweetness inhibitors based on the oleanane and dammarane skeletons. These saponins were isolated from the leaves of Gymnema sylvestre, Zizyphus jujuba and Hovenia dulcis [224]. Recently, antisweet oleanane-type saponins were isolated from Stephanotis lutchuensis vm. japonic a [225]. 

Clusiaceae (Guttiferae) is a family almost exclusively tropical in distribution and comprises about 40 genera and 1200 species most of which are woody [1], Extensive phytochemical studies have shown Clusiaceae to be a rich source of secondary metabolites including xanthones, triterpenoids, flavonoids, lactones and organic acids. In addition plants of this family produce a series of oxidized and polyisoprenylated benzophenones (PBDs), some of which are structurally complex and biologically active. 

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