Trichloroacetic acid warts

Carboxylic acids vary considerably in strength. Among the strongest is trichloroacetic acid (Ka = 0.20) a 0.10 M solution of C13C—COOH is about 73% ionized. Trichloroacetic acid is an ingredient of over-the-counter preparations used to treat canker sores and remove warts. 

Trichloroacetic acid 80-90% or bichlora-cetic acid 80-90% applied to warts repeat weekly if necessary or... 

Imiquimod 5% cream applied at bedtime three times weekly for up to 16 weeks" Cryotherapy with liquid nitrogen, or trichloroacetic acid or bichloracetic acid 80-90% as for external human papillomavirus warts repeat weekly as necessaiy Surgical removal (not for vaginal or urethral meatus warts)... 

Cryotherapy (e.g., liquid nitrogen or cryoprobe), or Podophyllin 10-25% in compound tincture of benzoin applied to lesions repeat weekly if necessary,or Trichloroacetic acid (TCA) 80-90% or bichloroacetic acid (BCA) 80-90% applied to warts repeat weekly if necessary, or... 

Trichloroacetic acid 40 % solution Non-sterile products (semisolids) Aqua dalibouri solution Cutaneous solution at therapy-resistant warts Indication, use Disinfectant, adstringent... 

It is widely used in biochemistry for the precipitation of macromolecules such as proteins, DNA and RNA. Its sodium salt is used as a weedkiller. Solutions containing trichloroacetic acid as an ingredient are used for cosmetic treatments such as chemical peels and tattoo removal and the treatment of warts, including genital warts. It can kill normal cells as well. It is considered safe for use for this purpose during pregnancy. 

MCA has nevertheless been suggested as a dermatological treatment for mosaic warts or periungual warts at a concentration of 80% or 60 g of MCA -I- 10 ml of water. Treating warts involves MCA coming into contact with a very limited area of skin, which explains the absence of poisoning when the treatment is carried out careMly. MCA has also been combined with salicylic acid and is considered more effective than dichloro- or trichloroacetic add in the treatment of warts. Because of this product s very high and potentially fatal toxicity, its use and indications should be strictly limited. 

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