Bichloroacetic acid

Dichloroacetic acid (Figure 12.4), also known as bichloroacetic acid and dichloroethanoic acid, has a molecular weight of 128.94 and a pK of 1.3. It is soluble in water, alcohol and ether. 

Cryotherapy (e.g., liquid nitrogen or cryoprobe), or Podophyllin 10-25% in compound tincture of benzoin applied to lesions repeat weekly if necessary,or Trichloroacetic acid (TCA) 80-90% or bichloroacetic acid (BCA) 80-90% applied to warts repeat weekly if necessary, or... 

Pregnancy Agents contraindicated in pregnancy include podofilox, fluorouracil, and podophyllin. Imiquimod is not approved for use in pregnancy, although it has been considered after signed consent has been obtained. Bichloroacetic and trichloroacetic acid have been used without problems. Ablative therapy is also a viable option. 

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