Cryotherapy with liquid nitrogen

Cryotherapy with liquid nitrogen can be performed to treat melasma with different results. It produces lightening of the pigmented areas that are as much significantly striking as they are superficial. 

Imiquimod 5% cream applied at bedtime three times weekly for up to 16 weeks" Cryotherapy with liquid nitrogen, or trichloroacetic acid or bichloracetic acid 80-90% as for external human papillomavirus warts repeat weekly as necessaiy Surgical removal (not for vaginal or urethral meatus warts)... 

Cryotherapy with liquid nitrogen or carbon dioxide snow is usually efficacious in very mild infestations, but it must be performed for a fair depth beyond the site of progression apparent at the visible lesion. Good results have also been obtained using topical thiabendazole in 10% suspension or 2% in dimethyl-sulfoxide. In cases characterized by diffuse lesions, oral thiabendazole at doses of 20-50 mg/kg/day for 7-10 days may be used (Stromberg and Christie 1976). 

Cryotherapy is a procedure used primarily for smaller, low-risk NMSCs with clearly defined margins. It involves delivering liquid nitrogen at subzero temperatures as a spray or with a supercooled metal probe to destroy the malignant tissue.5 It is contraindicated in metatypical or morpheaform BCC, in tumors that are invasive or recurrent, in hair-bearing skin that is susceptible to cryotherapy-induced alopecia, or in tumors with poorly defined borders. Cryotherapy is a cost-effective treatment that is easy for clinicians to deliver, but the recurrence rate is high with this procedure.5... 

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