Trichlorfon/metrifonate

Because of its high vapor pressure, dichlorvos is useful in the control of insects in closed spaces (e.g., warehouses, greenhouses, animal shelters, homes, and restaurants). It is available in oil solutions, emu-Isifiable concentrates, aerosols, and baits. Therapeutically, dichlorvos is used as a broad-spectrum anthelmintic (for destroying or expelling intestinal worms). It is also used as a feed through larvicide to control botfly larvae in the manure. It is primarily used for insect control. Dichlorvos is also a breakdown product of the organophosphorus pesticide trichlorfon (metrifonate). 

Oral 100 mg chewable tablets outside the USA, 100 mg/5 mL suspension Metrifonate (trichlorfon, Bilarcil)1 Niclosamide (Niclocide)1 Oxamniquine (Vansil, Mansil)1... 

Cummings JL, Ringman JM. Metrifonate (Trichlorfon) a review of the pharmacology, pharmacokinetics and clinical experience with a new acetylcholinesterase inhibitor for Alzheimer s disease. Expert Opin Investig Drugs 1999 8(4) 463-71. 

Metrifonate, see Trichlorfon Metriphonate, see Trichlorfon Metsulfu ron-methyl Meturon, see Fluometuron Meturon 4L, see Fluometuron Mevinphos... 

In vitro, metrifonate (trichlorfon) was slightly more effective in inhibiting the cholinesterase of mansoni than of haematobium, whereas in man, the drug is more effective against the latter species. 129 Arylvinylsulfones were active against S. man-soni in laboratory animals and monkeys. The most active compound (p-tert-butylvinylsulfone) caused dermatitis.130... 

Trichlorfon (ISO) is the same substance as metrifonate, the latter being the INN when used as a human pharmaceutical. 

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