Transgenes multiple expression

Feng, G., Mellor, R. H., Bernstein, M., Keller-Peck, C., Nguyen, Q. T., Wallace, M., et al. (2000) Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28, 41-51. 

Pilpel and Segal, 2004). This spine phenotype was also observed in transgenic mice expressing CA Racl in Purkinje cells (Luo et al., 1996). Such spines appear to be often engaged in multiple synaptic contacts, which is rarely seen in normal animals (Luo et al., 1996). On the other hand, expression of a DN Racl... 

Recently, the involvement of multiple mechanisms for hormonal regulation of lipolysis by HSL has convincingly been demonstrated with transgenic mice expressing human HSL in WAT [258]. HSL mRNA levels were increased in WAT by... 

Van Cott K, Lubon H, Russell C, et al. Phenotypic and genotypic stability of multiple lines of transgenic pigs expressing recombinant human protein C. Transgenic Res., 1997 6(3) 203-212. 

Further improvements to vims expression systems include trans-complementation of some of the virus functions from transgenic host plants (P12 plants for AlMV). By integrating parts of the viral vector into the plant chromosome, this system has the potential for multiple technical solutions that could overcome limitations of classical viral vectors [33]. Viral vectors can be used as molecular switches for tightly controlled, high-level transgene expression (Hull et al. unpublished data). 

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