Transcription features

Chromosomal organization, DNA replication, transcription, ribosome synthesis, and mitosis in plant cells are grossly similar to the analogous features in animals. 

Peroxisome Proliferator-Activated Receptors. Figure 1 Common structural and functional features of nuclear receptor transcription factors. Consistent with other members of the nuclear receptor superfamily, the PPARs have a modular domain structure consisting of domains A/B, C, D, and E. Each domain is associated with specific functions. 

The strict control of the activity of nuclear receptors by their respective ligands has recently permitted to follow the dynamics of DNA occupancy and to discover a surprising feature, which may be true also for other enhancer-binding factors. During transcriptional activation these transcription factors do not stably reside... 

The formation of the PIC described above is based on the sequential addition of purified components in in vitro experiments. An essential feature of this model is that the assembly takes place on the DNA template. Accordingly, transcription activators, which have autonomous DNA binding and activation domains (see Chapter 39), are thought to function by stimulating either PIC formation or PIC function. The TAF coactivators are viewed as bridging factors that communicate between the upstream activators, the proteins associated with pol II, or the many other components of TFIID. This view, which assumes that there is stepwise assembly of the PIC—promoted by various interactions between activators, coactivators, and PIC components— is illustrated in panel A of Figure 37-10. This model was supported by observations that many of these proteins could indeed bind to one another in vitro. 

SPECIAL FEATURES ARE INVOLVED IN REGULATION OF EUKARYOTIC GENE TRANSCRIPTION... 

Propst, F Rosenberg, M. P., Iyer, A., Kaul, K and Vande Woude, G. F. (1987). c-mos proto-oncogene RNA transcripts in mouse tissues structural features, developmental regulation, and localization in specific cell types. Mol. Cell. Biol. 7 1629-1637. 

The non-linear connections between DNA regions brought together by coiling and which are subject to control by transcription factors. These are then concentration-dependent cooperative features internal to the code. 

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