Transcription Factor Database

Ghosh, D. (1999). Object oriented Transcription Factors Database (ooTFD). Nucleic Acids Res 27,315-7. 

There are several transcription factor databases. Transfac [32] and TFD [10] provide databases of transcription factors, their binding sites and the genes which regulate these transcriptions. 

Gene sequence database. More than 20 other databases including SWISS-PROT, ACeDB, FlyBase, Eukaryotic Promoter Database, Restriction Enzyme Database, Transcription Factor Database, and CarbBank/CCSD. Databases and software development tools for sequence data available for anonymous ftp ncbi.nlm.nih.gov (130.14.25.1). 

All known transcription faaors are proteins except for a unique transcription factor (TFIIIR), for RNA Pol III in Bombyx mori, which is an isoleucine tRNA (33). This section provides an overview of the structural and functional characteristics of eukaryotic class II transcription factors which act on RNA Pol II and class II promoters. [Note For more extensive information on transcription factors and their properties, readers should consult the Transcription Factors Database (TFD) compiled by the National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.]... 

Sandelin, A., Alkema, W., Engstrom, P.,Wasserman, W. W., andLenhard, B. (2004) JASPAR an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res. 32, D91-D94. 

MetaBase is a curated database of human protein-protein and protein-DNA interactions, transcriptional factors, signaling, metabolism and bioactive molecules. MetaCore provides intuitive tools for data visualization, mapping and exchange, multiple networking algorithms and data mining. 

Certain short DNA sequences with lengths of 3-12 nucleotides can be defined as more or less stable sequence motifs. Many DNA motifs play a known functional role, e.g., promoter-binding sites for various transcription factors. The functions of other DNA motifs might be yet unknown. The variety of motif seqnences can be found in the scientific literature and databases or can be determined empirically (Table I). 

Target Information database - The Database contains information such as Protein-Protein interactions, Metabolic and Signaling Pathways, Transcription factors, post-Translational modifications, Disease information, various Drugs and Clinical compounds and the Companies of interest. 

Wingender E., Dietze P., Karas H., Knuppel R. (1996) TRANSFAC a database of transcription factors and their binding sites. Nucleic Acid. Res., 24, 238-241. 

One can search the consensus sequences of conserved motifs coming from the DoOP database. Either a shorter (for example, a transcription factor... 

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