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Traditional Strategies

Inventory—It is commonly used as a buffer to manage unpredictable supply and uncertain demand risks. However, inventory is expensive and may become a risk for high-tech products due to obsolescence. [Pg.375]

Capacity planning— This refers to the use of flexible production lines that can make multiple products and flexible workforce. For example, Toyota makes sure that their plants are flexible enough to supply multiple markets. This reduces idle capacity. HP uses a portfolio approach to workforce planning by maintaining a combination of full time, part time, and temporary workers. [Pg.375]

Dual sourcing—Use of two or more suppliers for critical parts is commonly used to avoid supply disruptions. HP follows the portfolio approach to vendors by maintaining a mix of suppliers from different geographic regions. [Pg.375]


An inherently safer process offers greater safety potential, often at a lower cost. However, selection of an inherently safer technology does not guarantee that the actual implementation of that technology will result in a safer operation than an alternate process which is inherently safer. The traditional strategy of providing layers of protection for an inherently more hazardous process can be quite effective, although the expenditure of resources to install and maintain the layers of protection... [Pg.18]

Whereas the utility of these methods has been amply documented, they are limited in the structures they can provide because of their dependence on the diazoacetate functionality and its unique chemical properties. Transfer of a simple, unsubstituted methylene would allow access to a more general subset of chiral cyclopropanes. However, attempts to utilize simple diazo compounds, such as diazomethane, have never approached the high selectivities observed with the related diazoacetates (Scheme 3.2) [4]. Traditional strategies involving rhodium [3a,c], copper [ 3b, 5] and palladium have yet to provide a solution to this synthetic problem. The most promising results to date involve the use of zinc carbenoids albeit with selectivities less than those obtained using the diazoacetates. [Pg.86]

R. Checa Moreno, E. Manzano, G. Miron, L.F. Capitan Vallvey, Comparison between Traditional Strategies and Classification Technique (SIMCA) in the Identification of Old Proteinaceous Binders, Talanta, 75 (3), 697 704 (2008). [Pg.258]

Genes are considered here as the basic elements (building blocks) that constitute a living organism (system). A traditional strategy to establish the structure—function (or sequence—function) relationship of... [Pg.383]

To meet shareholders expectations, U.S. and European pharmaceutical companies typically focus on leveraging products to manipulate their volume, price, and marketing portfolio in ever-changing equations to boost earnings. However, current industry pressures threaten the success of these traditional strategies. [Pg.42]

Selective enzymatic hydrolysis. The traditional strategy in sequence determination is to cut protein chains into smaller pieces which can be separated by chromatography or electrophoresis and sequenced individually. Enzymatic cleavage is especially useful because of its specificity. Trypsin, a so-called endo-... [Pg.116]

There are at least five knowledge-leveraging approaches that companies or business units can explore. All five entail a change in the way that chemical companies have traditionally thought about their businesses. Many will require much less capital than traditional strategies, but each can improve performance significantly. [Pg.33]

This new approach is currently receiving considerable attention in oceanography, and is a useful adjunct to the traditional strategies for analysis of tracer distributions and numerical models. A number of illustrative examples have been discussed in the literature (Deleersnijder ef al., 2001, 2002 Delhez et al, 2003 Haine and Hall, 2002 Hall and Haine, 2002). [Pg.3086]

First (Fig. 1(a)) the route may comprise two distinct sections, neither encroaching into the two-phase region, and each terminating in a reference macrostate. By reference macrostate we mean one whose partition function (and thus free energy) is already known - on the basis of exact calculation or previous measurement. The information accessible through MC study of the two sections of such a path has to be combined with the established properties of the reference macrostates to provide the desired link between the two equilibrium macrostates of interest. This is the traditional strategy for addressing the phase-coexistence problem. [Pg.47]

Pinkus and Chang (Section 1.4.2.1.1), in their search for orally applicable contraceptives, had decided upon norethindrone after some 200 steroidal candidates had been examined one by one. Chemists at Schering AG had stumbled upon drospirenone after some 600 newly prepared molecules with antialdosterone activity had become available [84]. It can be justifiably stated that the hardly ineffectual pharmaceutical industry had finished up in a blind alley in its search for new active substances by using traditional strategies [85]. [Pg.30]

It Is Interesting to note that. In some of the examples above, a kinetic approach Is appropriate which differs from the traditional strategy of defining composition and temperature dependence of reaction rates functions. Certain assemblies of complicated cellular reaction and regulation processes may be represented reasonably accurately under a variety of growth conditions In terms of timers, the Initiation points and durations of which may be dependent upon growth conditions. However, the above examples show that certain parameters associated with starting... [Pg.155]

Sweden, and Finland to determine that Canadian biomass pyrolysis technologies appear to be as good as any in the world, Canada has also had its pyrolysis oils upgraded and assessed by collaborators in the USA, Preliminary results indicate that Canada should review its traditional strategy of not immediately pursuing upgrading R D,... [Pg.11]


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