Toxicology assessment methods contribution

Power M, JR van der Meer, R Tchelet, T Egli, R Eggen (1998) Molecular-based methods can contribute to assessment of toxicological risks and bioremediation strategies. J Microbiol Methods 32 107-119. 

A brief discussion of each feature can be found later in this chapter. Underlying the epidemiological method are two assumptions first, that disease does not occur randomly and, second, that systematic study can identify factors that cause or can prevent disease (Hennekens and Buring 1987). Those design features help to ensure the scientific validity of human data, and they underscore the added strength and utility of epidemiological data that contribute to assessment of human health risk from toxicological hazards. 

Laws regulating toxic substances in various countries are designed to assess and control risk of chemicals to man and his environment. Science can contribute in two areas to this assessment firstly in the area of toxicology and secondly in the area of chemical exposure. The available concentration ( environmental exposure concentration ) depends on the fate of chemical compounds in the environment and thus their distribution and reaction behaviour in the environment. One very important contribution of Environmental Chemistry to the above mentioned toxic substances laws is to develop laboratory test methods, or mathematical correlations and models that predict the environ-... 

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