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Toxic and Medicinal Functions of Metal Ions Related to Biomacromolecules

D Toxic and Medicinal Functions of Metal Ions Related to Biomacromolecules [Pg.252]

Metal ions not only play a role in structure, transport or catalysis, but they may also have deleterious effects as a toxic metal (see above), or play an important role as a metal-containing drug or diagnostic agent. Examples of the last category are  [Pg.252]

Gold coordination compounds with S-donor ligands in the treatment of arthritis  [Pg.252]

A selection of such compounds has been redrawn in Fig. 4.4. Reviews on this matter are available.An example of our own work deals with the binding of platinum-antitumor compounds to DNA, and the resulting distortion of the DNA and its biological consequences will be discussed in some detail in the next section. [Pg.253]



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Biomacromolecules

Functional relation

Metal functions

Metal ion toxicity

Metal ions toxic

Metals and metal ions

Metals and toxicity

Metals, ions and

Related metals

Toxic ions

Toxic metals

Toxicity of metals

Toxicity, metal

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