Toxic agents nickel

Sunderman, F.W. 1970. Nickel poisoning. Pages 387-396 in F.W. Sunderman and F.W. Sunderman, Jr. (eds.). Laboratory Diagnosis of Diseases Caused by Toxic Agents. Warren H. Green, Inc., St. Louis, MO. 

SAFETY Tetracarbonylnickel(O) should be handled with extreme caution due to its volatility and high toxicity. All nickel compounds should be handled with care since many are cancer suspect agents. ]... 

The widespread use of many metals such as silver, cadmium, copper, mercury, nickel, lead, and zinc has resulted in their accumulation in the environment. Sediments are often the repositories of toxic metals (e.g.. Table 15-2). For example, copper is used as an anti-biofouling agent in marine paints and many harbor sediments contain markedly elevated levels of copper. 

Ni(CO)4 is the sole binary carbonyl complex of the elements of group 10 that is stable (Table 8.1). However, very few studies in which Ni(CO)4 is used in the preparation of catalysts have been reported [43]. This is probably due to the difficulty of manipulation of Ni(CO)4 and its very high toxicity. However, surface Ni(CO)4 species have been identified after the interaction of CO with highly dispersed supported nickel catalysts prepared by other routes [44]. Recent interest in the use of Ni(CO)4 has focused on the controlled production of nickel nanoparticles for specific purposes, such as in automotive converters [45]. The use of nickel tetracarbonyl as an agent for the nucleation process in the growth of single-wall carbon nanotubes has also been reported [46]. 

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