Tissue engineering distribution

Those anaiytioai systems where liposomes are used as artificial cell membranes to study body distribution mechanisms as efficient drug-delivery systems, controlled drug delivery, the synthesis of new biomaterial for tissue engineering and gene therapy are worthy of special mention. 

Microfabrication technique can also be utilized, in conjunction with tissue engineering, to spatially control cell distribution in a cell culture, which can be used to understand the cell shape dynamics, cell division, and cell-cell interactions. This information will be of significant use while engineering new materials for tissue regeneration and to develop biosensors of high sensitivity. 

Ndreu A, Nikkola L, Ylikauppila H, Ashammakhi N, Hasirci V (2008) Electrospun biodegradable nanofibrous mats for tissue engineering. Nanomedicine 3 45-60 Nelson T, Kaufman E, Kline E, Sokoloff L (1981) The extraneural distribution of gammahy-droxybutyrate. J Neurochem 37 1345-1388... 

Another useful thermal characterization technique is thermal compression in which a polymer fabric or biotextile is subjected to different loads at different temperatures. The thickness, pore size, and distribution can be monitored at each condition to prepare ideal scaffolds for tissue engineering. PolyCethylene terephthalate) (PET) nonwoven fiber scaffolds have been prepared for tissue engineering by thermal compression and simultaneous characterization. Applying pressure near the T of the polymer ( 70°C) yielded better control of the pore size distribution and smaller pore sizes, which led to faster and wider proliferation of Irophoblast andNIH 3T3 cells on the scaffold [9]. 

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