Overpressured thin layer chromatography

Nyiredy, S. Thin-layer (planar)/modes of development forced flow, overpressured layer chromatography and centrifugal. In Chromatography Cook, M., Poole, C.F., Eds. Academic Press New York, 2000 Vol. 2. 

Ferenczi-Fodor, K., Mincsovics, E., and Tyihak, E. (1991). Overpressured layer chromatography. In Handbook of Thin Layer Chromatography, J. Sherma and B. Fried (Eds.). Marcel Dekker, New York, pp. 155-181. 

Vuorela, P., Rahko, E.-L., Hiltunen, R., and Vuorela, H. (1994). Overpressured layer chromatography in comparison with thin layer and high performance liquid chromatography for the determination of coumarins with reference to the composition of the mobile phase. J. Chromatogr., A 670 191-198. 

Z. Witkiewics and J. Bladek, Overpressured thin-layer chromatography, J. Chromatogr., 373 111 (1986). 

At present attempts are being made to optimize the chromatography, and a great deal of faith has been placed in OPTLC (overpressured thin-layer chromatography). With this technique an extension of the development distance, better resolution and a shorter separation time are achieved. In 1982 a report was published on the applicability of this technique in the analysis of various substance groups 59). 

Hauck, H. E., W. lost Investigations and Results Obtained With Overpressured Thin-Layer Chromatography , J. Chromatogr. 262,113-120 (1983)... 

These limitations have led to the development of forced flow development systems and to the technique of overpressured thin layer chromatography. The special feature of this method is that the adsorbent layer is in a completely sealed unit and the solvent is delivered under pressure at a controlled oniform flow-rate by a pump module as in HPLC. Thus, overpressured TLC (OPTLC) takes place in the absence of a vapour pressure and the migration of the solvent front is free from both evaporation and adsorption effects. As the eluant is delivered under controlled conditions it is possible to optimise the separation conditions by adjusting the flow-rate of the eluant and also to undertake continuous development proeedures. 

Mazurek, M. Witkiewicz, Z. The analysis of organophosphorus warfare agents in the presence of pesticides by overpressured thin layer chromatography. J. Planar Chromatogr., 1991,4, 379-384. 

T3dhak, E. Mincsovics, E. Teten), P. Zamh6,1. Kalasz, H. Applicability of overpressured thin-layer chromatography in ph3ftochemistry. Acta Horticult. 1980, 96,113. 

Tyihak, E., E. Mincsovics, and H. Kalasz, 1979. New planar liquid chromatographic technique Overpressured thin-layer chromatography. > 1 4 75-81. 

Katy, Gy., Mincsovics, E., Szokan, Gy., and Tyihak, E. (1997). Comparison of thin layer chromatography and overpressured thin layer chromatographic techniques for the separation of ascorbigen and I -methylascorbigen. J. Chromatogr., A 764 103-109. 

Abraham, M., Polyak, B., Szajani, B., and Boross, L. (1983). Analytical separation of reduced and oxidized forms of glutathione from amino acid mixtures by overpressured thin-layer chromatography. J. Liq. Chromatogr. 6 2635-2645. 

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