Thiamin propyl disulfide

Thiamin therapy for alcoholics may involve a single injection oflO mg thiamin or 50 mg oral thiamin propyl disulfide. The latter compound is a fat-soluble version of thiamin that permits absorption of the vitamin where alcohol-induced damage would prevent efficient absorption of thiamin itself. Thiamin pnopyldisuT fide is converted in the body to thiamin. 

Nayakama, Y., 1959, Studies on the relationship between thiamine propyl disulfide and riboflavin on riboflavin content in the urine of normal children and in urine as well as blood of healthy infants under artificial feeding. Vitamins, 16 294-300. 

Thiamine propyl disulfide- s, a thiamine substitute (IX), was studied... 

Thiamin mononitrate is more stable in heat than thiamin hydrochloride for which reason it is often used for the thiamin fortification of cereal products that have to be cooked. Derivatives of thiamin, thiamin propyl disulfide... 

Synthetic allithiamin derivatives, such as thiamin propyl and tetrahydro-furfuryl disulfides, have been used for the prevention and treatment of thiamin deficiency. Because they are lipid soluble, and are not subject to the normal control of thiamin absorption by saturation of the intestinal transport system, they have potential benefits in the treatment of thiamin-deficient alcoholics, whose absorption of thiamin is impaired. 

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