Theory and technique of quantitative analysis

Part—I has three chapters that exclusively deal with General Aspects of pharmaceutical analysis. Chapter 1 focuses on the pharmaceutical chemicals and their respective purity and management. Critical information with regard to description of the finished product, sampling procedures, bioavailability, identification tests, physical constants and miscellaneous characteristics, such as ash values, loss on drying, clarity and color of solution, specific tests, limit tests of metallic and non-metallic impurities, limits of moisture content, volatile and non-volatile matter and lastly residue on ignition have also been dealt with. Each section provides adequate procedural details supported by ample typical examples from the Official Compendia. Chapter 2 embraces the theory and technique of quantitative analysis with specific emphasis on volumetric analysis, volumetric apparatus, their specifications, standardization and utility. It also includes biomedical analytical chemistry, colorimetric assays, theory and assay of biochemicals, such as urea, bilirubin, cholesterol and enzymatic assays, such as alkaline phosphatase, lactate dehydrogenase, salient features of radioimmunoassay and automated methods of chemical analysis. Chapter 3 provides special emphasis on errors in pharmaceutical analysis and their statistical validation. The first aspect is related to errors in pharmaceutical analysis and embodies classification of errors, accuracy, precision and makes... 

An early compilation of established quantitative infrared polymer/additive methods was published [164] no update seems to be available. Various reviews on quantitative (surface) IR analysis have appeared [18,130,159,165,166,166a]. Several textbooks discuss basic considerations concerning quantitative analysis by vibrational spectroscopy [167-169]. Data processing techniques for quantitative analysis are covered by Koenig [170], in particular regarding theory and application of FTIR to the characterisation of polymers. Hummel [171] has also discussed quantitative IR spectroscopic analysis of additives. 

Physical Methods in Chemical Analysis by W. G. Bert (Academic Press, 1950-61) is a survey in four volumes of quantitative analysis with a discussion of techniques, theory, apparatus and... 

The possibility of quantitative analysis with the ion probe is presently a matter of controversy. Although theories have been developed that aim to predict the strong matrix effects inherent in this technique and to correct for them, further work is required before the efficacy of these procedures of data evaluation can be definitely assessed. It is possible with calibration procedures, however, to obtain information on individual particles of micrometer size. " ... 

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