Ternary powder blends

The process starts with a pressed powder mixture of one or more binary borides of M -type metals and the metals required for the constituent of the ternary phase and for the binder phase. This method enables the fabrication of tailored M -M -solid solutions in the ternary boride as well as allows the introduction of high-performance Fe- or Ni-based alloys with exceptional properties. The metal powders are usually atomized alloys but may also consist of powder blends of the particular elements of interest. In Fig. 113 [360] the reaction process is schematically summarized showing the M alloy denoted as metal . In principle, the first step is the boronization of the powder particles by boron diffusion... 

Crystalline cellulose, hydroxypropyl cellulose, and Carbopol 934 have been studied in combination with lyophilized insulin as bioadhesive powder dosage forms for nasal delivery. Each formulation tested resulted in an decrease in plasma glucose level after nasal administration in dog and rabbit models. The most effective formulation, crystalline cellulose blended with insulin, decreased the plasma glucose level to 49% of the control value. In ternary systems the lyophilized Carbopol 934 and insulin blend with crystalline cellulose powder has been the most effective, leading to a hypoglycemia on the order of one-third of the effect obtained after intravenous injection of the same dose of insulin. The plasma glucose levels obtained in the volunteers after administration of the insulin-Carbopol-crystalline cellulose powder formulation were quite variable [38],... 

---