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Tablet tooling dimensions

Tablet SF, TS (in MPa), CS or pressure (in MPa), and friability were calculated from the tablet measurements, the compression forces, and the tooling dimensions. Plots of SF versus TS and TS versus CS were generated curves were fitted to the data and the properties at 0.85 SF and at the apex of the TS versus CS profile were determined. Tablet SF, TS (in MPa), CS or pressure (in MPa), and friability were calculated from the tablet measurements, the compression forces, and the tooling dimensions. Plots of SF versus TS and TS versus CS were generated curves were fitted to the data and the properties at 0.85 SF and at the apex of the TS versus CS profile were determined.
During tablet compression, the distance between the rollers remains constant unless a machine adjustment is made to change tablet hardness or thickness. Additionally, all tooling dimensions (tooling length and die cavity size) are constant within established standards. Under these conditions, for a specific material of uniform density, if the same volume of material is delivered to each die, the maximum measured compression force for each punch station is the same. If, on the other hand, different volumes of material are delivered to each die, the maximum measured compression force for each punch station is different. On this basis, adjustment of fill depth (fill volume) to maintain a constant compression force should result in a constant tablet weight. This concept is the general basis of all rotary tablet press force control systems. [Pg.3624]

The amount of clearance (space) between interacting parts like punch/die and barrel/turret guide, depends on the tolerance range (deviation from theoretical dimensions due to practical manufacturing reasons) of tooling dimensions. The clearance between the die wall and the punch tip affects the tableting process as well as the mechanical properties of the finished product while the powder is compressed, air needs to be released, and when the compressed tablet is moved upwards within the die bore, friction on the die walls is affected by the clearance. [Pg.3782]

Standardization of tooling dimensions has been agreed to facilitate interchangeability between presses and to reduce the number of spare parts. In many cases, a certain press is available with different turrets in order to standardize tooling within a tablet manufacturing company irrespective of the make of tablet presses used... [Pg.3783]

The physical strength of a tablet is also dependent on its dimensions. In the construction of a force-strength profile, all tablets will have the same cross-sectional area as the same tooling will have been used. However, as the compressive force is changed, so will the tablet height. Hence, comparisons made on the basis of breaking strength will not be truly valid. [Pg.3668]

One level of relatively thin tablets or parts with any contour (class I of P/M Figure 187 2) an be pressed with a single punch and force may be applied from one side. The maximum dimension A (Figure 187) depends on the particulate feed and the shape of the compact. Thicker parts (class II of P/M Figure 188), while still requiring only simple tooling, must be pressed from two directions. Holes are obtained by the installation of mandrels or core rods. [Pg.230]


See other pages where Tablet tooling dimensions is mentioned: [Pg.1150]    [Pg.1151]    [Pg.1154]    [Pg.1160]    [Pg.3782]    [Pg.3783]    [Pg.3784]   
See also in sourсe #XX -- [ Pg.3784 ]




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Tablet tooling

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