Synthesis via Grafting-through Approach

the distinct domains of the resulting hybrid polymer are responsible for the self-assembly of the material. It should be noted that there are several other approaches to nanomaterials via ROMP, including the synthesis of dispersed latex nanoparticles, [29-34] hybrid nanoparticles via scaffolded initiation [35-39], and nanoparticles encapsulated in polymer matrices [40,41]. Amphiphilic micellar nanoparticles are by far the most prevalent systems in the literature relevant to a discussion of ROMP in nanoparticle synthesis, particularly those fully characterized in terms of particle formation and morphological characterization of the resulting polymer aggregates. Amphiphilic copolymers synthesized by ROMP that are not studied in this manner [42-45] or those nanoscale architectures involving only covalent interactions [46, 47] are not discussed here. 

Highly stable random poly(HNBEMQ-r-HNBEMO) 

In most instances, ROMP is utilized to arrange monomer blocks sequentially into distinct amphiphilic domains in order to create a polymer capable of self-assembly. In this way, one can vary the hydrophobic tail length and hydrophilic head size in order to create a wide range of morphologies. Shunmugam and coworkers [84] have shown that homopolymers comprised of only one type of 

67 mol% poly[(HNBEMQ)5oo-r-(HNBEMO)25o], (c) 75 mol% polyKEINBEMQjyjQ-r-(HNBEMO)25q], and (d) 80mol% poly[(HNBEMQ),ooo-t-(HNBEMO)25o]. All were prepared from ethanol/methylene chloride (2/1, v/v). (Reprinted from Ref. [54].) 

In more recent work, Nguyen and coworkers [77] demonstrated that preformed micelles could be decorated in a similar manner using bio-orthogonal copper-catalyzed cHck chemistry. 

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