Swiss peptides

Besides their interesting color application values, betalainic plants are also worthwhile from a nutritional standpoint. Research on this topic has recently been resumed with great scientific vigor in both in vitro and in vivo studies on red beets, amaranth, red-colored Swiss chard, red-violet pitahayas, and especially cactus pears. ° In the future, betalainic color crops will be benchmarked because of their pigment structure and quantity and also because of the individual and synergistic activities of their components such as colorless phenolics, amino compounds, peptides, proteins, and hydrocolloids. 

Zernig G, Troger J, Saria A (1993) Different behavioral profiles of the non-peptide substance P (NKl) antagonists CP-96,345 and RP 67580 in Swiss albino mice in the black- and-white box. Nemosci Lett 151 64-66... 

DOTATATE) with and lutetium ( Lu). The quality control and purification procedures are also described. Biodistribution studies were performed in normal Swiss mice and in nude mice bearing AR42J tumours. In vitro studies were used to evaluate the affinity of the radiopharmaceuticals for somatostatin receptors in rat brain cortex and tumour cells. Saturation binding and the internalization of the labelled peptides were determined. The frequency of micronuclei in peripheral blood lymphocytes exposed to different radioactive concentrations of [ IJDOTATATE and [ Lu]DOTATATE was evaluated by micronucleus assay. 

Table 3.7 gives the biodistribution data of DOTATATE in two groups of Swiss mice those that received the radiopharmaceutical obtained at a molar peptide to radionuclide ratio of 0.54, and those that received the agent obtained at a molar peptide to radionuclide ratio of 2.73. 

Increasing reproducibility of available separation techniques and sensitivity and affordability of mass spectrometers, as well as the desire and need to automate the identification process, have caused peptide mass fingerprinting and MS/MS sequencing to gain importance and to become the method of choice for many proteomics laboratories. Several tools are available to assist users in the interpretation of mass spectrometry data. Peptldent (http //www.expasy.org/tools/peptident.html) on the ExPASy server follows the concept of the other tools from the ExPASy proteomics suite, in that it takes into account annotation available in the SWISS-PROT/TrEMBL database, in particular as post-translational modifications and processing are concerned. The user can paste peptide masses (monoisotopic or average) into the Peptldent form, but peptide mass data can also be uploaded from a file on the user s local computer. Supported file formats are .pkm ... 

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